| 吴棪,陈乔尔.肿瘤免疫逃逸的相关分子及其作用机制研究[J].安徽医药,2016,20(4):621-625. |
| 肿瘤免疫逃逸的相关分子及其作用机制研究 |
| Mechanism and related molecules of tumor immune escapeWU Yan, CHEN Qiao-er (Stomatologic Hospital ﹠College,Anhui Medical University,Key LaboratoryofOral Diseases Research of Anhui,Hefei,Anhui 230032,China)Abstract: |
| 投稿时间：2015-12-09 |
| DOI： |
| 中文关键词: 肿瘤 免疫逃逸 淋巴细胞 Fas/FasL |
| 英文关键词: tumor immune escape lymphocyte Fas/FasL 考文献: |
| 基金项目:安徽省自然科学基金(No 1508085MH155) |
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| 中文摘要: |
| 免疫逃逸是肿瘤细胞逃避机体杀伤作用的重要途径。肿瘤细胞可通过多种途径逃避机体免疫系统的监视,如Fas/FasL(Fas Ligand)反击、诱导免疫细胞凋亡或者抑制免疫细胞增殖等。因此,该文对免疫逃逸的机制及相关分子进展进行研究,可能发现更为有效地治疗方法,缓解病人的痛苦。 |
| 英文摘要: |
| Immune escape of tumor cells is an important way to evade the body’s killing.Tumor can adopt different mechanisms of immune escape,such as Fas/ FasL(Fas Ligand) counterattack, inducing immune cell apoptosis,immune cell proliferation inhibition,etc.Studies on the mechanism of immune escape and its related molecules make it possible to find more effective treatments to relieve pain of cancer patients. |
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