| 刘员员,洪浪.CHADS2评分在不同冠脉病变严重程度的非房颤患者中发生卒中的预防意义[J].安徽医药,2016,20(5):907-910. |
| CHADS2评分在不同冠脉病变严重程度的非房颤患者中发生卒中的预防意义 |
| Value of CHADS2 score to predict the incidence of stroke in patients of differently severity coronary artery disease without atrial fibrillationLIU Yuan-yuan,HONG Lang (The People’s Hospital of Jiangxi,Nanchang,Jiangxi 330000,China) Abstract:Objectives |
| 投稿时间：2016-02-12 |
| DOI： |
| 中文关键词: 冠心病/并发症 卒中 创伤严重度指数 CHADS评分 |
| 英文关键词: Coronary Disease / complications Stroke Trauma Severity Indices Value of CHADS |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨CHADS2评分指导非房颤的不同冠脉病变严重程度患者卒中的预防意义。 方法 回顾性分析非房颤的冠心病患者211例,并按CHADS2评分分别分为三组:0~1分(A组)78例、2分(B组)70例、3~6分(C组)63例,并分别按Gensini评分分为两组:A组(≤20分组)68例、(＞20分组)10例;B组(≤20分组)48例、(＞20分组)22例；C组(≤20分组)20例、(＞20分组)43例;且随访所有患者出现卒中情况。 结果 B组、C组比A组患者Gensini评分更可能＞20分,差异有统计学意义(P<0.01),C组与B组患者比较Gensini评分更可能＞20分,差异有统计学意义(P<0.01),余非房颤的冠心病患者随访期间出现卒中的52例,C组与A组、B组比较发生卒中的概率更大,差异有统计学意义(P<0.01)；B组与A组比较发生卒中的概率无明显差异,差异无统计学意义(P>0.05)；且CHADS2评分分组对卒中的影响比较,以卒中为因变量,以CHADS2评分0~1分为对照组,CHADS2评分3~6分组比CHADS2评分0~1分组发生卒中的可能性大,0R值2.068 (95%CI为1.375~3.674),提示CHADS2评分3~6分组发生卒中的可能性是CHADS2评分0~1分组2.068倍。 结论 CHADS2评分是非房颤的不同冠脉病变程度的患者是否发生卒中的独立预测危险因素,为冠心病患者更早的联用抗凝药物的治疗提供依据。 |
| 英文摘要: |
| Objectives To discuss the value of CHADS2 score to predict the incidence of stroke in patients of differently severity coronary artery disease without atrial fibrillation. Methods To retrospectively analysis 211 cases,According to CHADS2 score,The patients were divided into three groups:0 and 1 group(78 cases )(group A),2 group(70 cases) (group B),3~6 group (63 cases) (group C),and According to the Gensini score,Every group was respectively divided into two groups:group A(≤20 group) 68 cases and (>20 group) 10 cases);Group B(≤20 group ) 48 cases,(>20 group) 22 cases);Group C (≤20 group) 20 cases,(>20 group)43 cases);then follow-up the incidence of stroke with all patients. Results Gensini score of group Cand group Bcompared with that of group Aare more likely to higher than 20 points,the difference was statistically significant (P<0.01),Gensini score of group Ccompared with that of group Bare more likely to higher than 20 points,the difference was statistically significant (P<0.01),52 cases of all the patients have stroke during the period of follow-up.group Ccompared with group Aand group Bhad higher probability of stroke,the difference was statistically significant (P<0.01)；Probability of stroke between group Band group Ahas not obvious difference,the difference was not statistically significant (P>0.05),and the CHADS2 score was independent risk factor of stroke in the patients of differently severity coronary artery disease without atrial fibrillation,CHADS2 score 0~1 was divided into control group,CHADS2 score 3 to 6 group compared with CHADS2 score 0~1 group was higher the possibility of stroke,OR was 2.068 (95% CI 1.375~3.674),the possibility of stroke in CHADS2 score 3 to 6 group was 2.068 times than the possibility of stroke in CHADS2 score 0~1 group. Conclusion The CHADS2 score was independent risk factor of stroke in the patients of differently severity coronary artery disease without atrial fibrilliation to provide the reference opinion for the treatment to add in anticoagulant drugs in the patients of coronary heart disease. |
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