| 王谋云.中药杀胚Ⅰ号方联合甲氨蝶呤治疗剖宫产瘢痕部位妊娠的临床疗效观察[J].安徽医药,2016,20(8):1584-1586. |
| 中药杀胚Ⅰ号方联合甲氨蝶呤治疗剖宫产瘢痕部位妊娠的临床疗效观察 |
| Clinical efficacy of early pregnancy in cesarean section scar patients treated by traditional Chinese medicine killing embryos formula Ⅰ with methotrexate |
| 投稿时间：2016-03-23 |
| DOI： |
| 中文关键词: 妊娠,异位 瘢痕 流产,治疗性/方法 甲氨蝶呤 中药疗法 |
| 英文关键词: Pregnancy,ectopic Cicatrix Abortion,therapeutic/methods Methotrexate Drug therapy(TCD) |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨中药杀胚Ⅰ号方联合甲氨蝶呤(MTX)治疗剖宫产后瘢痕部位妊娠(CSP)的临床疗效。方法 将44例CSP的患者,按分层随机化分组法分为观察组与对照组各22例。对照组在超声引导下将MTX局部注射到孕囊,待血HCG降至2 000 IU·L-1以下,再予清宫术；观察组在超声引导下将MTX局部注射到孕囊的基础上开始口服中药杀胚Ⅰ号方,待血HCG降至2 000 IU·L-1以下,再予清宫术,比较两组的临床疗效。 结果 观察组的治疗效果显著高于对照组(P＜0.05)；观察组的血β-HCG降低至2 000 IU·L-1以下的时间以及子宫下段超声正常时间均较对照组显著缩短(P＜0.05)；两组之间不良反应发生率差异无统计学意义(P＞0.05)。结论 中药杀胚Ⅰ号方联合MTX治疗CSP疗效显著,突显中医优势,值得临床推广应用。 |
| 英文摘要: |
| Objective To investigate the efficacy of traditional Chinese medicine killing embryos formula Ⅰ combined with methotrexate(MTX) on treating patients of early pregnancy with cesarean section scar(CSP).Methods Totally44 CSP patients were randomized into two groups.The control group(n=22) was prescribed with conventional treatment alone,injected with methotrexate(MTX) into the gestational sac guided by ultrasound technique,then uterine curettage was carried out when β-HCG decreased to less than 2 000 IU·L-1.The treatment group (n=22) received conventional medical therapy plus killing embryos formula Ⅰ,then uterine curettage was carried out whenβ-HCG decreased to less than 2 000 IU·L-1.Results The clinical efficacy rate of the treatment group was significantly higher than the control group (P＜0.05).The time needed for the β-HCG in the treatment group decreased to less than 2 000 IU·L-1 and the time needed for ultrasonic detection of lower uterine segment displaying normal were significantly shorter than those in the control group (P＜0.05).There was no significant difference in the incidence of adverse reactions between the 2 groups.Conclusions Killing embryos formula Ⅰ combined with MTX showed favorable effect on the treatment of CSP,which is worthy of clinical promotion. |
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