| 吴军.醒后脑卒中患者临床特点及短期预后分析[J].安徽医药,2016,20(12):2294-2296. |
| 醒后脑卒中患者临床特点及短期预后分析 |
| Clinical characteristics and short-term prognosis in hospitalized patients with wake-up stroke |
| 投稿时间：2016-06-18 |
| DOI： |
| 中文关键词: 醒后脑卒中 睡眠 临床特点 |
| 英文关键词: Wake-up stroke Sleep Clinical characteristics |
| 基金项目: |
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| 中文摘要: |
| 目的 初步了解探讨醒后脑卒中(WUS)的临床特点,提高对WUS的认识。方法 采用回顾性研究,收集住院急性期脑梗死患者184例,按照WUS定义对所有入组患者分为WUS组和非醒后脑卒中(NWUS)组,登记脑血管病危险因素及相关实验室指标,并按入院时美国国立卫生研究院卒中量表评分(NHISS)和发病2周时改良Rankin量表(mRS)评分,评价疾病严重程度及短期预后,比较WUS与NWUS的临床特点、脑血管危险因素及短期预后的异同。 结果 WUS组有短暂性脑缺血发作(TIA)病史者高于NWUS组(22.0% vs 7.0%,P<0.05),WUS组入院时NHISS评分高于NWUS组(7[4,9]vs 5[3,8],P＜0.05)。发病2周时mRS评分,WUS组高于NWUS组(3[2,4] vs 2[2,4],P<0.05)。结论 WUS患者有病前TIA发作史比例相对较高,其他脑血管病危险因素与NWUS无明显差异；WUS早期病情相对较重,更易发生出血转化,短期预后较差。 |
| 英文摘要: |
| Objective To explore clinical features and short-term prognosis of wake-up stroke.Methods A retrospective cohort study was adopted in 184 hospitalized patients with acute cerebral infarction.Those patients were assigned into the WUS group and non-during sleep cerebral infarction group(NWUS).We analysed cerebrovascular disease risk factors and laboratory parameters,and used admission NHISS scores and mRS scores two weeks after stroke attack to evaluate the severity of the disease and short-term prognosis,and to compare the clinical characteristics,cerebral vasucular risk factors and short-term prognosis of WUS with those of NWUS.Results The proportion of patients with history of TIA in WUS group was higher that NWUS group (22.0% vs 7.0%,P<0.05).The admission NHISS scores in WUS group was significantly higher than NWUS group(7 [4,9]vs 5 [3,8],P<0.05).mRS scores two weeks after stroke attack in WUS group was higher than NWUS(3 [2,4]vs 2 [2,4],P<0.05).Conclusions WUS patients had a higher incidence of premorbid TIA history,and may be more serious than NWUS patients.Hemorrhagic transformation was more common,and short-term prognosis maybe even worse. |
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