文章摘要
覃艳琼,万鸿,万里鹏,等.免疫肠内营养支持对老年重症脑卒中病人营养状况和免疫功能的影响[J].安徽医药,2017,21(1):133-135.
免疫肠内营养支持对老年重症脑卒中病人营养状况和免疫功能的影响
Effect of immune enteral nutrition support on nutritional status and immune function in elderly patients with severe stroke
投稿时间:2016-05-23  
DOI:
中文关键词: 重症脑卒中  老年人  营养状况  免疫功能
英文关键词: Severe stroke  Aged  Nutritional status  Immune function
基金项目:
作者单位
覃艳琼 华中科技大学同济医学院附属梨园医院老年病科,湖北 武汉 430070 
万鸿 黄冈市中心医院肿瘤科,湖北 黄冈 438000 
万里鹏 黄冈市中心医院肿瘤科,湖北 黄冈 438000 
沈莹 华中科技大学同济医学院附属梨园医院老年病科,湖北 武汉 430070 
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中文摘要:
      目的探讨免疫肠内营养支持对老年重症脑卒中病人营养状况和免疫功能的影响。方法 选择66例老年重症脑卒中病人,按照随机数字表法将其分为观察组和对照组各33例,观察组给予免疫肠内营养支持治疗,对照组给予常规院内营养支持治疗,对比两组病人在治疗前、治疗后第1及第2周时病人的营养状况和免疫功能指标的变化情况。结果 治疗第1周及第2周后,观察组IgG、IgM、IgA及CD4+、CD8+水平较同时间段的对照组为优,差异有统计学意义(P<0.05),两组治疗第2周时IgG、IgM、IgA及CD4+、CD8+指标均显著优于治疗前,差异有统计学意义(P<0.05);观察组在治疗第1周及第2周时的总蛋白(TP)、总胆固醇(TC)、甘油三酯(TG)及血红蛋白(Hb)水平较同时间段的对照组为优,差异有统计学意义(P<0.05),两组治疗第2周时TP、TC、TG及Hb指标均显著低于治疗前,差异有统计学意义(P<0.05)。结论 对于老年重症脑卒中病人而言,应用免疫肠内营养支持不仅可在一定程度上显著改善病人的营养状况,而且还能提高病人机体免疫力,值得临床推广应用。
英文摘要:
      Objective To explore the effect of enteral nutrition support on nutritional status and immune function in elderly patients with severe stroke. Methods Sixty six cases of elderly patients with severe stroke were divided into the observation group and the control group according to the random number table method,with 33 cases in each group.The patients of the observation group were given enteral immune nutrition support treatment,and the patients of the control group were given routine hospital nutritional support treatment and before treatment.After 1 and 2 weeks treatment,nutritional status and immune function changescomparison of two groups were compared. Results After 1 week and 2 weeks treatment,IgG,IgM,IgA and CD4+ and CD8+ of the observation group were higher than that of the control group,and the difference was statistically significant (P<0.05).After 2 weeks treatment,IgG,IgM,IgA and CD4+,CD8+ of these two groups were significantly elevated,the difference was statistically significant (P<0.05) while TP,TC,TG and Hb levels of the observation group were also improved compared with the control group,and the difference was statistically significant (P<0.05).Meanwhile,TP,TC,TG and Hb of two groups were significantly lower than that before treatment,and the difference was statistically significant (P<0.05). Conclusion For the elderly patients with severe stroke,the application of immune enteral nutrition support can not only significantly improve the nutritional status of patients in a certain extent,but also improve the immunity of the patients,which is worth of clinical application.
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