| 周红,胡容峰,桂赟,等.胶囊型渗透泵控释制剂的研究进展[J].安徽医药,2017,21(6):983-986. |
| 胶囊型渗透泵控释制剂的研究进展 |
| Research progress of controlled-release osmotic pump capsules |
| 投稿时间：2016-11-30 |
| DOI： |
| 中文关键词: 缓控释制剂 恒速释药 渗透泵 胶囊 |
| 英文关键词: |
| 基金项目:国家自然科学基金项目(81573615) |
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| 摘要点击次数: 6220 |
| 全文下载次数: 1364 |
| 中文摘要: |
| 渗透泵制剂作为目前应用最广和前景较好的缓控释制剂,具有长时间恒速释药、不受胃肠道因素影响、体内外相关性良好等优点,主要包括片剂、胶囊剂等。与渗透泵片剂相比,渗透泵胶囊具有诸多优势,因而受到药物制剂工作者的广泛关注。该文通过查阅近几年国内外相关文献和专利,分类综述了胶囊型渗透泵控释制剂的研究现状。 |
| 英文摘要: |
| Osmotic pump preparation is the most widely used sustained-controlled release preparation with good future.It could control drug release with constant speed and avoid the influence from the circumstance of gastrointestinal tract.Besides,the release character in vitro of osmotic pump has good correlation with absorption in vivo.Osmotic pump preparation mainly includes tablets,capsules and so on.Compared with the osmotic pump tablets,osmotic pump capsules have many advantages and have received widespread attention.In this article,the research status of controlled-release osmotic pump capsules is reviewed by retrieving the relevant literature and patents in recent years. |
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