| 李庚,吴巧稚,顾刘宝.2型糖尿病病人他汀类药物使用单中心横断面分析[J].安徽医药,2017,21(6):1134-1136. |
| 2型糖尿病病人他汀类药物使用单中心横断面分析 |
| A single center sectional analysis of statins used inpatients with type 2 diabetes |
| 投稿时间：2016-10-11 |
| DOI： |
| 中文关键词: 冠心病 糖尿病,2型 降血脂药 他汀类药物 |
| 英文关键词: Coronary heart disease Diabetes mellitus type 2 Antilipemic agents Statin drug |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨2型糖尿病病人他汀类药物使用及血脂达标情况,以分析糖尿病病人他汀类药物使用现状。方法 收集2型糖尿病住院的需使用他汀类药物治疗病人670例,根据入院信息收集病人一般情况,按是否患有冠心病分为未合并冠心病组(G1组)545例和合并冠心病组(G2组)125例,然后分别测定总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C),对该类病人入院时他汀类药物使用情况及达标情况进行统计描述和分析。结果 2型糖尿病病人入院前他汀类药物使用率为41.8%,LDL-C达标率52.8%。G1组他汀类药物使用率33.6%明显低于G2组他汀类药物使用率77.6%,但LDL-C达标率上G1组明显高于G2组。结论 2型糖尿病病人的他汀类药物使用率偏低,同时LDL-C达标率也不理想,2型糖尿病病人合并冠心病人群的LDL-C达标率更低,这需要临床药师更加关注病人他汀类药物的使用。 |
| 英文摘要: |
| Objective To study the change of blood lipid levels by using statins in patients with type 2 diabetes mellitus and analyze the use of statin drug in patients with diabetes mellitus.Methods 670 cases of type 2 diabetes inpatients with hypoglycemic drugs treatment were chosen.The patients were divided as diabetes combined without coronary heart disease(CHD) group (G1,5 cases) and diabetes combined with CHD group (G2,5 cases) according to whether they had CHD or not.General information were recorded,according to admission information of patients.Then the level of total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C) and low density lipoprotein cholesterol(LDL-C) were examined.The result of statin usage and qualification compliance rate in patients were statistically analyzed.Results The rate of statins use was 41.8% in inpatients with type 2 diabetes before admission,the success rate of LDL-C was 52.8%.G1 group matching the selected criteria with 33.6% taking statin drugs were significantly lower than G2 group with 77.6% statin taking.But G1 group was significantly higher than G2 group in the success rate of LDL-C.Conclusion The rate of statin use in patients with type 2 diabetes was low,at the same time,success rate of LDL-C is not ideal.The success rate of LDL-C in patients with type 2 diabetes combined with the coronary heart disease (CHD) was lower,which means clinical pharmacists should pay more attention to the use of statins in patients. |
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