| 张迎生,朱瑞,李邦松,等.孤立性脑桥梗死急性期病情进展与不同影像学分型的相关性分析[J].安徽医药,2017,21(12):2210-2213. |
| 孤立性脑桥梗死急性期病情进展与不同影像学分型的相关性分析 |
| The progressive acute isolated pontine infarction is related to its different imaging types |
| 投稿时间：2017-05-01 |
| DOI： |
| 中文关键词: 进展性脑桥梗死 影像学分型 |
| 英文关键词: Progressive pontine infarction Imaging types |
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| 中文摘要: |
| 目的 探讨急性脑桥梗死病情进展的相关因素。方法 连续收集66例急性脑桥梗死患者的临床及头颅影像学资料,根据病情是否进展分为进展组和非进展组,依据头颅磁共振弥散加权成像(DWI)检查结果,分为旁正中梗死、深部小梗死和其他类型梗死。比较进展组与非进展组之间的临床和头颅影像学资料,然后进一步回归分析急性脑桥梗死病情进展的相关因素。结果 66例脑桥梗死患者中发生病情进展17例,未进展49例,进展发生率25.8%；进展组与非进展组之间临床资料差异无统计学意义,两组之间脑白质疏松程度亦差异无统计学意义,上、中、下不同部位脑桥梗死在两组之间构成比差异无统计学意义(P=0.41),旁正中梗死、深部小梗死和其他类型梗死不同影像学分型在两组之间构成比方面差异有统计学意义(χ2=9.416,P=0.011),其中旁正中梗死在进展性脑桥梗死中发生率高于非进展组；相关性分析显示较其他2种类型脑桥梗死旁正中梗死与进展性脑桥梗死之间显著相关(r=0.376,P=0.002)；进展性脑桥梗死相关因素 Logistic 回归分析显示,脑桥梗死不同影像学分型与病情进展明显相关(P=0.04),表现为旁正中梗死较其他类型梗死发生病情进展的概率显著增加(OR=0.13,P=0.02),较脑桥深部小梗死,旁正中梗死发生病情进展的趋势可能同样存在(OR=0.23,P=0.10)。结论 脑白质疏松严重程度与脑桥梗死病情进展无明显相关；不同影像学分型脑桥梗死与病情是否进展之间显著相关,旁正中梗死患者更容易在急性期出现病情进展。 |
| 英文摘要: |
| Objective To investigate the factors related to the isolated progressive pontine infarction (PPI).Methods The clinical and brain MRI of 66 patients with acute pontine infarction treated were collected and analyzed retrospectively.Patients were further assigned into PPI and non-PPI group according to their clinical manifestations.According to the results of magnetic resonance diffusion weighted imaging (DWI),the pontine infarction were assigned into paramedian,well-circumscribed small deep infarction and other.The clinical and brain MRI data were analyzed and compared between PPI and non-PPI group.Then,the factors related to the progressive acute isolated pontine infarction were further analyzed.Results The 66 cases of pontine infarction patients were enrolled including 17 cases in the PPI group and 49 cases in the non-PPI group.The incidence of PPI was 25.8%.There was no significant difference in clinical data between the PPI and the non-PPI group;the severity of leukoaraiosis was not significantly different between the two groups;there was no significant difference in upper,middle and lower parts of pontine infarction between the two groups (P=0.41).But,there was significant difference between the two groups in the different imaging types of pontine infarction (χ2=9.416,P=0.011).Among them,the incidence rate of paramedian infarction in PPI group was higher than that in non-PPI group.Compared with the other 2 imaging types of pontine infarction,the correlation analysis showed that there was a significant correlation between the paramedian infarction and the PPI (r=0.376,P=0.002).Logistic regression analysis showed that there was a significant correlation between the different imaging types of pontine infarction with the PPI (P=0.04).The incidence rate of the paramedian infarction in PPI group was increased significantly compared with other types of pontine infarction (OR=0.13,P=0.02),the trend of which maybe also existed compared with the small deep infarction (OR=0.23,P=0.10).Conclusions The severity of leukoaraiosis and the PPI were not related.There was a significant correlation between the different imaging types of the pontine infarction and the PPI,and the patients with the paramedian infarction were more likely to develop the PPI. |
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