| 肖光荣,王鹤定,毛宜虎,等.肺部感染病原菌分布及耐药性分析[J].安徽医药,2018,22(2):331-334. |
| 肺部感染病原菌分布及耐药性分析 |
| Pathogens distribution and drug resistance analysis of pulmonary infectionXIAO Guangronga,WANG Hedingb,MAO Yihua,LI Meiqinga,XU Yuna,FANG Shuqinga,SHENG Jiayana (a.Department of Intensive Care Unit,b.Department of Medical Laboratory,Renhe Hospital,Baoshan,Shanghai 200431,China) Abstract:Objective |
| 投稿时间：2016-12-21 |
| DOI： |
| 中文关键词: 肺部感染 病原菌 耐药性 |
| 英文关键词: pulmonary infection pathogenic bacteria drug resistance |
| 基金项目: |
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| 中文摘要: |
| 目的探讨肺部感染致病菌类型及耐药性特点,为临床合理使用抗生素提供依据。 方法回顾性分析重症医学科(ICU)及呼吸内科肺部感染患者的痰病原菌细菌谱及药物敏感性试验结果。 结果ICU共分离出病原菌1 281株,其中革兰阴性菌占76.7%,革兰阳性菌占16.1%,革兰阳性菌中耐甲氧西林金黄色葡萄球菌(MRSA) 152株,占革兰阳性菌73.8%。革兰阴性菌中,铜绿假单胞菌所占比例最高,其次为黏质沙雷菌和鲍氏不动杆菌。呼吸内科共分离出病原菌852株,其中革兰阴性菌占72.8%；革兰阳性菌占21.4%。 结论ICU及呼吸内科肺部感染患者的病原菌均以革兰阴性菌为主,且ICU较呼吸内科所占比例更高。两者均呈多重耐药。革兰阳性菌以金黄色葡萄球菌为主。了解细菌种类分布和耐药趋势,对合理使用抗生素有指导意义。 |
| 英文摘要: |
| Objective To explore the pathogenic bacteria types and drug resistance characteristics of pulmonary infection and to provide references for clinical reasonable application of antibiotics.Methods Retrospective analysis of bacteria spectrum of sputum pathogen and drug sensitivity test in patients with pulmonary infection,who were hospitalized in departments of ICU and respiratory medicine. Results In ICU,1 281 strains of pathogens were isolated.The ratio of gram-negative bacteria was 76.7%,gram-positive bacteria was 16.1%.There were 152 methicillin-resistant Staphylococcus aureus (MRSA) in gram-positive bacteria,accounting for 73.8%.Among gram-negative bacteria,the ratio of Pseudomonas aeruginosa was the highest,followed by Serratia marcescens and Acinetobacter baumannii.In department of respiratory medicine,852 strains of bacteria were isolated,including 72.8% gram-negative bacteria and 21.4% gram- positive bacteria. Conclusions In departments of ICU and respiratory medicine,gram-negative bacteria were main pathogen of pulmonary infection.The ratio of ICU was higher than that in the department of respiratory medicine.Both of these infection were characterized by multi drug resistance.Staphylococcus aureus was the mainly gram-positive bacteria.Understanding the distribution of bacterial species and drug resistance trend play an important role to guide rational use of antibiotics. |
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