| 杨帅帅,孙玉凯,崔景利,等.SiewertⅡ型和Ⅲ型食管胃结合部腺癌淋巴结转移规律分析[J].安徽医药,2018,22(6):1051-1054. |
| SiewertⅡ型和Ⅲ型食管胃结合部腺癌淋巴结转移规律分析 |
| Lymphatic metastasis of siewert type Ⅱ and Ⅲ adenocarcinomas of the esophagogastric junction |
| 投稿时间：2016-11-19 |
| DOI： |
| 中文关键词: 胃肠肿瘤 淋巴转移 胃切除术 预后 |
| 英文关键词: Gastrointestinal neoplasms Lymphaticmetastasis Gastrectomy Prognosis |
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| 中文摘要: |
| 目的 探讨SiewertⅡ型和Ⅲ型食管胃结合部腺癌(AEG)的淋巴结转移规律。 方法 回顾性分析2006年1月至2010年12月潍坊市人民院医院收治的190例食管胃结合部腺癌患者的临床病理资料,分析SiewertⅡ型和Ⅲ型淋巴结转移规律。 结果 190例胃癌患者中,SiewertⅡ型83例,SiewertⅢ型107例。SiewertⅡ型AEG以第1、2、3、4、7和19组淋巴结转移为主,其转移率分别为56.6%,51.8%,56.6%,31.3%,54.2%和22.9%。SiewertⅢ型AEG以第1、2、3、4、7和8a组淋巴结转移为主,其转移率分别为58.9%,57.9%,67.3%,43.9%,39.3%和21.5%。SiewertⅡ型与SiewertⅢ型相比在第6、8a、9、11、12、14组淋巴结转移率低,而在第7、19组淋巴结转移率高,差异有统计学意义(均P<0.05)。SiewertⅡ型和SiewertⅢ型5年生存率分别为33.9%和34.5%,差异无统计学意义(χ2=0.504,P=0.478)。SiewertⅡ型AEG无淋巴结转移患者5年生存率为53.3%,有淋巴结转移者为26.9%,差异无统计学意义(χ2=3.020,P=0.082)。SiewertⅢ型AEG无淋巴结转移患者5年生存率为63.9%,有淋巴结转移者为30.1%,差异有统计学意义(χ2=5.640,P<0.05)。 结论 SiewertⅡ型和Ⅲ型食管胃结合部腺癌的预后无差异。SiewertⅡ型AEG以第1、2、3、4、7和19组淋巴结转移为主；SiewertⅢ型AEG以第1、2、3、4、7和8a组淋巴结转移为主,两型淋巴结转移有差别。 |
| 英文摘要: |
| Objective To investigate the different patterns of lymphatic metastasis of Siewert type Ⅱ and Ⅲ adenocarcinomas of the esophagogastric junction (AEG). Methods Data of 190 patients with gastric cancer who underwent gastrectomy from January 2006 to December 2010 in Weifang People's Hospital were retrospectively analyzed.Statistical analysis was performed to identify the pattern of lymphatic metastasis. Results There were 190 adenocarcinoma of the esophagogastric junction (AEG) patients,including Siewert type Ⅱ (83 cases) and Siewert type Ⅲ (107 cases).Siewert type Ⅱ AEG was mainly associated with lymph node metastasis in groups 1,2,3,4,7 and 19,with metastasis rates of 56.6%,51.8%,56.6%,31.3%,54.2% and 22.9%,respectively.Siewert type Ⅲ AEG was mainly composed of lymph node metastasis in groups 1,2,3,4,7 and 8a,with metastasis rates of 58.9%,57.9%,67.3%,43.9%,39.3% and 21.5%,respectively.Compared with Siewert type Ⅲ AEG,the metastatic rates of Siewert type Ⅱ AEG in groups 6,8a,9,1,12,and 14 were significantly lower,while the metastatic rates of Siewert type Ⅱ AEG in groups 7 and 19 were significantly higher (all P<0.05).The 5-year survival rates of the Siewert type Ⅱ and Siewert Ⅲ were 33.9% and 34.5% respectively,without significant difference (χ2=0.504,P=0.478).The 5-year survival rates of Siewert type Ⅱ AEG patients with and without lymph node metastasis were 26.9% and 53.3%,without significant difference (χ2=3.020,P=0.082).The 5-year survival rates of Siewert type Ⅲ AEG patients with and without lymph node metastasis were 30.1% and 63.9%,with significant difference (χ2=5.640,P<0.05). Conclusions The prognosis of Siewert typeⅡ and Ⅲ AEG was not different.Siewert type Ⅱ AEG was mainly associated with lymph node metastasis in groups 1,2,3,4,7 and 19.Siewert type Ⅲ AEG was mainly associated with lymph node metastasis in groups 1,2,3,4,7 and 8a.There were differences in lymph node metastasis of Siewert typeⅡ and Ⅲ AEG. |
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