| 郭安平,沈爱宗.某医院门诊超说明书用药情况调查与分析[J].安徽医药,2018,22(9):1847-1850. |
| 某医院门诊超说明书用药情况调查与分析 |
| Analysis and evaluation of the off-label drug use in outpatient department of a hospital |
| 投稿时间：2017-11-03 |
| DOI： |
| 中文关键词: 超说明书用药 药品说明书 合理用药 |
| 英文关键词: Off-label drug use Medication specifications Rational drug use |
| 基金项目: |
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| 摘要点击次数: 1950 |
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| 中文摘要: |
| 目的 了解某医院门诊超说明书用药情况并进行处方分析,促进临床安全合理用药。方法 分层随机抽取某医院2014年9月至2015年2月每月门诊处方共3 000张,以药品说明书为依据,对超说明书用药情况进行统计和分析。结果 统计出超说明书处方278张,占抽取处方总数的9.27%。其中排名前三位的超说明书用药类型是超适应证用药,占31.65%；超给药剂量,占28.78%；超给药频次,占16.55%。超说明书用药前三位的科室是皮肤科(26.62%)、消化科(19.06%)、妇产科(17.63%)。结论 该院门诊超说明书用药比例较高,建议加强制度规范和采取防范措施减少超说明书用药的安全风险。 |
| 英文摘要: |
| Objective To understand the situation of the off-label drug use in outpatient department of our hospital and provide reference for the rational drug use.Metheod A total of 3 000 prescriptions were randomly collected in outpatient department of our hospital from Sep.2014 to Feb.2015.The behavior of off-label drug use was statistically analyzed according to the drug instructions.Results There were 278 (9.27%) off-label drug use prescriptions.The problems such as extra-indications (31.65%),overdose(28.78%),extra-DDDs (16.55%) were the top-three types of off-label use.And,the skin department (26.62%),the gastroenterology department (19.06%),Obstetrics and Gynecology (16.83%) occupied the top three of all the prescription departments.Conclusion The conditions of off-label drug use are common in outpatient department of our hospital.It is necessary to establish off-label drug use regulations,so as to reduce the risk of medication. |
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