| 刘学进,陈垦.双歧杆菌三联活菌胶囊联合肠内营养治疗急性重症胰腺炎的临床观察[J].安徽医药,2018,22(10):2008-2010. |
| 双歧杆菌三联活菌胶囊联合肠内营养治疗急性重症胰腺炎的临床观察 |
| A clinical observation of bifidobacterium triple viable capsules combined with enteral nutrition in the treatment of acute severe pancreatitis |
| 投稿时间：2017-03-19 |
| DOI： |
| 中文关键词: 胰腺炎,急性坏死性 肠道营养 有益菌种 |
| 英文关键词: Pancreatitis,acute necrotizing Enteral nutrition Probiotics |
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| 中文摘要: |
| 目的 观察对急性重症胰腺炎患者采用双歧杆菌三联活菌胶囊联合肠内营养进行治疗的效果。 方法 选取 66例急性重症胰腺炎患者作为研究对象,按照随机数字表法将其分为两组,每组33例,分别为使用双歧杆菌三联活菌胶囊联合肠内营养治疗的观察组和仅使用早期肠内营养治疗的对照组。观察两组间胰腺炎CT分级评分、白细胞数、肿瘤坏死因子α(TNF-α)、白细胞介素-8(IL-8)、C-反应蛋白(CRP)、乳酸脱氢酶(LDH)、脂肪酶和淀粉酶差异性。 结果 与对照组的总有效率(75.76%)相比,观察组的总有效率(93.94%)明显更高,差异有统计学意义(P=0.039),其各项血液检测指标和CT评分均优于对照组。 结论 对重症胰腺炎患者采用双歧杆菌三联活菌胶囊联合肠内营养进行治疗能促进其治疗效果的提高,为临床治疗胰腺炎提供一种可借鉴的处理措施。 |
| 英文摘要: |
| Objective To observe the therapeutic effect of bifidobacterium triple viable capsules combined with enteral nutrition treatment on patients with severe acute pancreatitis. Methods Sixty-six cases of acute severe pancreatitis patients were enrolled as the research objects, and according to random number method,they were assigned into two groups, 33 cases for respective groups.The observation group used bifidobacterium triple viable capsules with enteral nutrition therapy while the control group used only early enteral nutrition therapy.The differences in pancreatitis CT grading score,white blood cells,TNF-α,IL-8, CRP,LDH,lipase and amylase between the two groups were observed and analyzed. Results Compared with the total effective rate of the control group (75.76%), the total effective rate (93.94%) of the observation group was significantly higher (P=0.039),and all blood tests results and CT scores were better than those of the control group with significant difference. Conclusions For patients with severe acute pancreatitis the use of bifidobacterium triple viable capsules combined with enteral nutrition therapy can improve its therapeutic effect,which provides a selective therapy for acute severe pancreatitis. |
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