| 王蕾,张毅,严红燕,等.基于三维打印技术制作钛合金修复体修补兔颅骨缺损的研究[J].安徽医药,2018,22(11):2106-2107. |
| 基于三维打印技术制作钛合金修复体修补兔颅骨缺损的研究 |
| 3D printing prefabricated individual titanium alloy to repair rabbit skull defect |
| 投稿时间：2017-12-06 |
| DOI： |
| 中文关键词: 三维打印技术 颅骨缺损 修复 新西兰兔 |
| 英文关键词: Three-dimensional printing Skull defect Repair New Zealand rabbit |
| 基金项目:南通市科技计划项目(MS12015109,MS12015016) |
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| 摘要点击次数: 2004 |
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| 中文摘要: |
| 目的 通过三维(3D)打印技术协助新西兰兔个体化钛合金修复体进行预制行颅骨缺损修补,探讨3D技术在颅骨缺损重建中的运用价值。方法 选取健康雄性新西兰兔12只制作颅骨缺损模型成功后,螺旋64排CT薄层无间距逐层扫描获得断层数据后进行格式转换构建三维颅骨立体模型,利用3D打印机进行修复体的三维原型制造,结合模型利用钛合金修复体进行骨性缺损区域精准修补。结果 钛合金修复体与骨性缺损区域及边缘组织契合满意,术中一次固定到位,避免反复剪裁,操作阻力小,伤口均一期愈合,不良反应较少,未观察到颅内感染、头皮溃烂、钛合金外露、排出及移位等不良现象。术后颅骨外形与健侧相比更美观、功能修复满意,并邀请三位同行医师评估修复满意度,以100%为满意,取平均值,满意率为98.78%。结论 与颅骨缺损修补术相比,3D打印技术可快速、精准结合钛合金,对个体化修复颅骨缺损区尤其是复杂解剖形态“适形”可能更胜一筹,值得临床推广运用。 |
| 英文摘要: |
| Objective To use 3D printing to prefabricate the New Zealand rabbit individualized titanium alloy prosthesis for the accurate repair of skull defect,and to explore the value of 3D printing in reconstruction of skull defect.Methods Twelve healthy male rabbits were selected to make brain defect model,and the computed tomography data were obtained by 64-slice spiral CT scanning.Three-dimensional skull model was constructed and produced with 3D printer.The defect area was repaired by using the titanium alloy prosthesis combined with the three-dimensional model and titanium screws.Results Titanium alloy prosthesis was satisfied with the area and edge tissue of bone defect.It was fixed at one time,avoiding repeated cutting,having small operation resistance.The wound healed at phase Ⅰ,with fewer adverse reactions.No side effects were observed including intracranial infection,scalp ulceration,titanium alloy exposure,discharge and displacement.After the operation,the shape of the skull was well-done compared to the healthy side,and the functional repair was satisfactory.Three colleagues were invited to evaluate the satisfaction degree of the repair.The satisfaction value was set at 100%,and the average satisfaction rate was 98.78%.Conclusion Compared with the current skull defect repair,3D printing technology adopted for titanium alloy individualized repair,especially for the conformality of complicated anatomic from,may be superior,which is worthy of clinical promotion. |
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