| 张伟,孙梦雯,严光,等.血管性痴呆伴肺部感染患者营养不良的临床特点及危险因素分析[J].安徽医药,2018,22(12):2335-2338. |
| 血管性痴呆伴肺部感染患者营养不良的临床特点及危险因素分析 |
| Clinical characteristics of patients with vascular dementia complicated with pulmonary infection and malnutrition and analysis of risk factors |
| 投稿时间：2018-05-28 |
| DOI： |
| 中文关键词: 血管性痴呆 肺部感染 营养不良 临床特点 危险因素 |
| 英文关键词: Vascular dementia Lung infections Malnutrition Clinical characteristics Risk factors |
| 基金项目:国家自然科学基金(81401815) |
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| 摘要点击次数: 1975 |
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| 中文摘要: |
| 目的 探讨血管性痴呆伴肺部感染患者营养不良的临床特点及危险因素,为临床诊疗提供依据,以降低营养不良的发生率。 方法 连续收集2016年12月至2017年12月在安徽省立医院老年科治疗的135例80岁以上血管性痴呆伴肺部感染住院患者临床资料进行回顾性分析,按照肺部感染营养不良的诊断标准进行筛选,分析其临床特点并根据病情进行危险因素分析。 结果 135例患者中符合营养不良的为75例,发生率为55.6％。与营养正常组比较,营养不良组年龄偏大(t=3.159,P=0.002),卧床人数偏多(χ2=20.821,P<0.001),鼻饲人数偏多(χ2=5.868,P=0.015),厌食人数偏多(χ2=8.861,P=0.003),半年感染大于3次人数较多(χ2=7.502,P=0.006),抗生素使用人数较多(χ2=10.445,P=0.001),得到家人照顾人数偏少(χ2=18.482,P<0.001),淋巴细胞计数偏低(t=3.159,P=0.002)。 多变量logistic回归分析显示,年龄[优势比(OR)0.806,5%置信区间(CI)0.706～0.921;P=0.001]、卧床 (OR 3.627,5% CI 1.372～5.075;P=0.016)、抗生素(OR 4.306,5% CI 1.614～8.771;P=0.017)、家人照顾(OR 0.174,5% CI 0.031～0.968;P=0.046)、半年感染大于3次(OR 0.045,5% CI 0.003～0.754;P=0.031)和淋巴细胞计数(OR 2.752,5% CI 1.214～6.237;P=0.015)均为血管性痴呆伴肺部感染营养不良的独立危险因素。 结论 血管性痴呆伴肺部感染与自身发生营养不良之间相互影响且相互制约,临床应针对相应的危险因素,采取积极地预防对策,改善患者的预后。 |
| 英文摘要: |
| Objective To explore the clinical characteristics of the patients with vascular dementia complicated with pulmonary infection and malnutrition and analyze the risk factors so as to provide basis for clinical diagnosis and treatment to reduce the incidence of malnutrition. Methods The clinical data of 135 cases of patients aged over 80 with vascular dementia complicated with pulmonary infection and malnutrition who were treated in the geriatric department from December 2016 to December 2017 were retrospectively analyzed.The subjects were screened according to the diagnostic standard of pulmonary infection complicated with malnutrition,and the clinical characteristics and the risk factors were observed. Results Of 135 cases of patients,the malnutrition occurred in 75 cases with the incidence rate of 55.6％.The mean age of the malnutrition group was older than that in the non-malnutrition group (t= 8.014,P<0.001) (χ2=5.868,P=0.015).The number of patients staying in bed (χ2=20.821,P<0.001),nasogastric tube feeding(χ2=5.868,P=0.015),anorexia was much more(χ2=8.861,P=0.003).The number of patients infected more than three times in half a year was much more (χ2=7.502,P=0.006) and the number of patients using antibiotics was on the higher side (χ2=10.445,P=0.001).The number of patients taken care of by their families was on the lower side(χ2=18.482,P<0.001);the lymphocyte count was lower(t=3.159,P= 0.002).The multivariate logistic regression analysis showed that age (odds ratio 0.806,5% confidence interval 0.706-0.921;P=0.001),staying in bed (OR 3.627,5% CI 1.372-5.075;P=0.016),using antibiotics (OR 4.306,5% CI 1.614-8.771;P= 0.017),being taken care of by their families (OR 0.174,5% CI 0.031-0.968;P=0.046),being infected more than three times in half a year (OR 0.045,5% CI 0.003-0.754;P=0.031) and lymphocyte count (OR 2.752,5% CI 1.214-6.237;P=0.015) were the independent risk factors for vascular dementia complicated with pulmonary infection and malnutrition. Conclusion There are mutual influences and constraints between patients with vascular dementia complicated with pulmonary infection and malnutrition.It is necessary for the clinic to take effective prevention counter-measures aiming at the corresponding risk factors. |
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