| 欧月秀,秦曙光,林昌平,等.血液透析病人自体动静脉内瘘失功能危险因素的 logistic回归分析[J].安徽医药,2019,23(1):72-75. |
| 血液透析病人自体动静脉内瘘失功能危险因素的 logistic回归分析 |
| Logistic regression analysisof risk factors for dysfunction of autologous arteriovenous fistula in hemodialysis patients |
| 投稿时间：2017-06-23 |
| DOI： |
| 中文关键词: 肾透析 动静脉瘘 血栓形成 糖尿病 C反应蛋白质 血小板计数 失功能 Logistic回归分析 |
| 英文关键词: Renal dialysis Arteriovenous fistula Thrombosis Diabetes mellitus C-reactive protein Platelet count Dysfunction Logistic regression analysis |
| 基金项目:海南省自然科学基金(20168306) 血液透析病人自体动静脉内瘘失功能危险因素的 logistic回归分析 欧月秀1,秦曙光2,林昌平3,王转镇4(1.广州医科大学内科学专业,广东 广州 511436；2.广州市第一人民医院肾内科,广东 广州 510180；3.海南省第三人民医院肾内科,海南 三亚 572000；4.海南医学院第一附属医院肾内科,海南 海口 570102) |
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| 中文摘要: |
| 目的 分析血液透析(HD)病人自体动静脉内瘘(AVF)失功能的独立危险因素。方法 回顾性分析2013年1月至2016年5月在海南省第三人民医院行HD的病人248例的临床资料,先经单因素分析发生失功组和通畅组的相关因素差异,将有差异的因素经多因素logistic回归分析,找出发生AVF失功能的独立危险因素。结果 248例HD病人发生AVF失功能的病人55例,比例22.18%。通畅组原发病为糖尿病的比例、低血压比例、开始透析年龄、压迫时间、纽扣式穿刺法比例、血栓病人比例、血小板(PLT)水平、三酰甘油(TG)水平、C反应蛋白(CRP)水平、甲状旁腺激素(PTH)水平均低于失功组(均P<0.05)。经logistic回归分析显示,糖尿病、低血压、开始透析年龄、压迫时间、血栓形成、PLT、TG和CRP为HD病人发生AVF的独立危险因素(均P<0.05)。结论 低血压、年龄增加、压迫时间长、血栓、高PLT水平、高TG水平和高CRP水平均增加HD病人AVF失功能的概率。 |
| 英文摘要: |
| ObjectiveTo analyze the independent risk factors for dysfunction of autologous arteriovenous fistula (AVF) in hemodialysis (HD) patients.Methods 248 HD patients from January 2013 to May 2016 were used as research material and analyzed retrospectively.The difference of correlation factors of dysfunction group and patency group were analyzed by the univariate analysis.Logistic regression analysis was used to get independent risk factors of dysfunction of AVF in HD patients.Results 55 patients with AVF dysfunction occurred in 248 patients with HD and the proportion was 22.18%.The ratio of primary disease to be diabetes and hypotension,age of dialysis initiation,compression time,button puncture ratio,thrombus proportion,platelet (PLT) level,triglyceride (TG) level,C reactive protein (CRP) level,parathyroid hormone (PTH) level of patency group all were lower than those of dysfunction group(all P<0.05).Logistic regression analysis showed hypotension,age of dialysis initiation,compression time,thrombosis,PLT,TG,and CRP levels were the independent risk factors for AVF dysfunction in patients with HD(all P<0.05).Conclusion Hypotension,increasing age,longer compression time,thrombosis,higher PLT,higher TG,and higher CRP levels can increase the risk of AVF dysfunction in patients with HD. |
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