| 黄德晗,司方圆,刘才远.飞秒制瓣准分子激光原位角膜磨镶术和前弹力层下激光角膜磨镶术术后角膜前表面高阶相差变化的比较[J].安徽医药,2019,23(1):102-105. |
| 飞秒制瓣准分子激光原位角膜磨镶术和前弹力层下激光角膜磨镶术术后角膜前表面高阶相差变化的比较 |
| Comparison of higher-order aberration changes in anterior corneal surface between FS-LASIK and SBK surgery |
| 投稿时间：2017-02-13 |
| DOI： |
| 中文关键词: 角膜磨镶术,激光原位 激光,准分子 角膜波前像差 像差测量 飞秒激光 高阶像差 |
| 英文关键词: Keratomileusis,laser in situ Lasers,excimer Corneal wavefront aberration Aberrometry Femtosecond laser Higher-order aberrations |
| 基金项目:飞秒制瓣准分子激光原位角膜磨镶术和前弹力层下激光角膜 磨镶术术后角膜前表面高阶相差变化的比较黄德晗1,司方圆2,刘才远3 (1.宣城市中心医院眼科,安徽 宣城 232400；2.安徽医科大学第一附属医院眼科,安徽 合肥 230022；3.中国科学技术大学医院眼科,安徽 合肥 230026) |
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| 中文摘要: |
| 目的 比较飞秒制瓣准分子激光原位角膜磨镶术(FS-LASIK)和机械刀辅助的前弹力层下激光角膜磨镶术(SBK)术后角膜前表面高阶像差的变化情况。方法 选择2015年9月至2016年8月在宣城市中心医院行角膜屈光手术病人112例,通过随机数字表法分为FS-LASIK的54例病人(54只眼)和行SBK术的58例病人(58只眼),其中每例病人随机数字表法选择1只眼。于术前及术后3个月利用眼前节全景仪(Pentacam HR)测量病人角膜前表面的高阶像差(主要包括总的高阶像差、水平彗差、垂直彗差及球差),高阶像差的描述采用Zernike多项式表示。结果 FS-LASIK组和SBK组术前病人在年龄、等效球镜度数(SE)、角膜前表面各高阶像差的比较均差异无统计学意义(P>0.05)。FS-LASIK组术后3个月的角膜前表面总的高阶像差和球差较术前差异有统计学意义(P<0.001),水平及垂直彗差较术前均差异无统计学意义(P值分别为0.558和0.325)。SBK组术后3个月角膜前表面总的高阶像差、球差(P<0.001)及垂直彗差(P=0.001)较术前差异有统计学意义,水平彗差较术前差异无统计学意义(P=0.428)。FS-LASIK组和SBK组在术后3个月时的总的高阶像差、水平慧差及球差值均差异无统计学意义(P值分别为0.487、0.373和0.063),然而两组之间的垂直彗差差异有统计学意义[FS-LASIK:(-0.03±0.48) μm,SBK:(-0.21±0.42) μm；P=0.030]。结论 FS-LASIK术组与SBK术组在角膜前表面的总高阶像差、水平慧差和球差之间均差异无统计学意义,然而FS-LASIK术后3个月的角膜前表面垂直彗差显著低于SBK组,可能表明在对称性、偏中心、倾斜等方面,飞秒激光制瓣优于机械板层角膜刀制瓣。 |
| 英文摘要: |
| Objective To make a comparison of higher-order aberration changes in anterior corneal surface between femtosecond laser-assisted keratomileusis (FS-LASIK) and sub-bowman-keratomileusis (SBK surgery).Methods One hundred and twelve patients were randomly divided into FS-LASIK gourp and SBK group according to the random number table method.FS-LASIK was performed in 54 eyes of 54 patients,and 58 eyes of 58 patients received mechanical SBK (selected eye was chosen from each of the patients by random number table method).HOAs (included total HOAs,horizontal coma aberration,vertical coma aberration,and spherical aberration) were measured preoperatively,after 3 months postoperatively by Pentacam.The aberrations were described as Zernike polynomials.Results There was no significant difference between FS-LASIK group and SBK preoperative patients in age,spherical equivalent (SE),higher-order aberrations of corneal surface (P>0.05).Total HOAs and SA increased significantly in 3 months after FS-LASIK(P<0.001).However,no significant difference was found in postoperatively vertical coma and horizontal coma (P=0.558 & 0.325).Total HOAs,SA (P<0.001),and vertical coma (P=0.001) showed a significant growth in SBK group.However,there was no significant change in horizontal coma.No significant difference was found between FS-LASIK group and SBK group in postoperatively total HOAs,SA and horizontal coma (P=0.487,0.063 and 0.373,respectively).However,signifcant difference was found in postoperatively vertical coma (FS-LASIK:-0.03±0.48μm；SBK:-0.21±0.42μm；P=0.030).Conclusion FS-LASIK increased less vertical coma than SBK after 3 months postoperatively which may illustrated that Flaps created by femtosecond laser has more advantages than microkeratome in irregular,decentration,and tilt. |
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