| 张娟,袁建军,杨会杰,等.超声检查对孕11～13+6周胎儿开放性脊柱裂的诊断价值[J].安徽医药,2019,23(5):936-938. |
| 超声检查对孕11～13+6周胎儿开放性脊柱裂的诊断价值 |
| The diagnostic value of ultrasound for fetal open spina bifida in 11～13+6 weeks gestation |
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| DOI：10.3969/j.issn.1009-6469.2019.05.026 |
| 中文关键词: 囊肿性脊柱裂 超声检查,产前 颈部透明带检查 孕龄 妊娠结局 妊娠初期 |
| 英文关键词: Spina bifida cystica Ultrasonography,prenatal Nuchal translucency measurement Gestational age Pregnancy outcome Pregnancy trimester,first |
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| 中文摘要: |
| 目的 探讨运用超声检查筛查对孕11～13+6周胎儿开放性脊柱裂(OSB)的诊断价值。方法 选取2017年4月至2018年2月在郑州大学人民医院行常规颈项透明层(NT)检查的7 683例孕妇为研究对象,在正中矢状切面上测量胎儿颅内透明层(IT)厚度、脑干直径(BS)与脑干-枕骨间距离(BSOB),并计算出BS/BSOB值;严重的胎儿畸形建议行染色体检查并选择终止妊娠,余神经系统阴性孕妇继续妊娠,行中晚孕期系统超声检查并追踪其妊娠结局及引产结果。结果 对孕11～13+6周胎儿行系统超声检查筛查出OSB共16例(0.208%),合并露脑畸形2例,无脑畸形2例,全前脑1例,肢体畸形1例,心脏畸形1例,侧脑室扩张4例,体蒂异常1例。早孕期正常,中晚孕期行系统超声检查发现OSB共4例(0.052%),其中2例合并侧脑室扩张。结论 对孕11～13+6周胎儿行系统性超声检查可筛查出OSB,对早期诊断OSB有重要意义;与中晚孕期胎儿超声检查筛查相结合,可更好筛查胎儿OSB。 |
| 英文摘要: |
| Objective To evaluate the clinical value of ultrasonography screening in the diagnosis of fetus open spina bifida (OSB) in 11～13+6 weeks.Methods 7683 pregnant women who were underwent routine Nuchal Translucency examination by ultrasonography screening in People’s Hospital of Zhengzhou University from April 2017 to February 2018 were enrolled in this study.The thickness of fetal intracranial hyaline layer (IT),the diameter of brain stem (BS) and the distance between the brain stem and occipital bone (BSOB) were measured on the median sagittal section,and BS/BSOB was calculated.serious malformed fetus was suggested to check the chromosomes and selected to terminate the pregnancy.The pregnant women with the negative residual nerve system continued pregnancy,ultrasonography screening in the middle and late pregnancy was carried out to track the outcome of pregnancy and induction of pregnancy.Results A total of 16 cases (0.208%) of OSB were detected by ultrasonography screening during 11～13+6 weeks gestation,including 2 cases of exencephaly,2 cases of anencephaly,1 case of holoprosencephaly,1 case of limb deformity,1 case of cardiamorphia,4 cases of lateral ventricle dilatation and 1 case of body stalk anomaly.Fetuses were normal in the first trimester,4 cases (0.052%) of OSB were detected by ultrasonography screening in the second and third trimester,including 2 cases of lateral ventricle dilatation.Conclusions OSB can be detected by ultrasonography screening in 11～13+6 weeks gestation,which is of important significance for the first trimester of OSB.Combining with ultrasonography screening in the second and third trimester,fetal OSB can be better screened. |
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