| 董沛晶,王志芳,王慧.口服乳糖酶对婴幼儿轮状病毒肠炎80例的临床疗效影响[J].安徽医药,2019,23(6):1244-1246. |
| 口服乳糖酶对婴幼儿轮状病毒肠炎80例的临床疗效影响 |
| Effect of oral lactase on clinical efficacy of rotavirus enteritis in 80 infants |
| 投稿时间：2018-05-13 |
| DOI： |
| 中文关键词: 乳糖酶 婴幼儿病毒性肠 疗效 |
| 英文关键词: Lactase Infantile viral enteritis Efficacy |
| 基金项目: |
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| 中文摘要: |
| 目的 分析乳糖酶对婴幼儿轮状病毒肠炎临床疗效的影响,为该病提供有效的辅助治疗方法。方法 选择莎车县人民医院儿科病房住院2017年1月25日至2018年4月1日明确诊断婴幼儿轮状病毒肠炎病人160例,依据随机数字表法随机分为对照组和观察组,每组80例。观察组在对照组常规治疗基础上再口服乳糖酶制剂,以腹泻、呕吐、发热及腹胀等症状消失的时间作为疗效判断指标,对各组病例的疗效情况进行分析。结果 口服乳糖酶时间＜3 d时,对照组和观察组的总有效率分别为32.50%和36.25%,差异无统计学意义(χ2=0.249,P=0.618);口服乳糖酶时间≥3 d时,对照组和观察组的总有效率分别为77.50%和95.00%,差异有统计学意义(χ2=10.329,P=0.001)。观察组口服乳糖酶＜3 d和≥3 d间比较,差异有统计学意义(χ2=61.20,P=0.000)。结论 口服乳糖酶对婴幼儿轮状病毒肠炎治疗具有明显辅助作用,但作用显现至少需要口服时间达到3 d,应该引起临床重视。 |
| 英文摘要: |
| ObjectiveTo analyze the effect of lactase on the clinical efficacy of infant rotavirus enteritis,and to provide an effective adjuvant treatment for the disease.Methods A total of 160 infants with rotavirus enteritis diagnosed in Department of Paediatrics,The People's Hospital of Shache County from January 25,7 to April 1,8 were selected and randomly assigned into the control group and the observation group according to the random number table method,with 80 cases in each group.The observation group received oral lactase preparations in addition to conventional treatment also adopted in the control group.The time of disappearance of symptoms such as diarrhea,vomiting,fever and bloating was used as the efficacy judgment indicator,and the curative effect of each group was analyzed.Results When the oral lactase time was <3 d,the total effective rates of the control group and the observation group were 32.50% and 36.25%,respectively.The difference was not statistically significant (χ2=0.249,P=0.618).When the oral lactase time was ≥3 d,the total effective rates of the control group and the observation group were 77.50% and 95.00%,respectively,and the difference was statistically significant (χ2=10.329,P=0.001).There was a statistically significant difference between oral lactase intake <3 d and ≥3 d in the observation group (χ2=61.20,P=0.000).Conclusion Oral lactase has a significant auxiliary effect on the treatment of infantile rotavirus enteritis,but the effect won't appear until after 3 days of oral administration,which should be attached importance to in clinic. |
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