| 江万仓.临床No期非小细胞肺癌病人术后病理检查为N12期淋巴结转移的相关因素分析[J].安徽医药,2019,23(7):1373-1375. |
| 临床No期非小细胞肺癌病人术后病理检查为N12期淋巴结转移的相关因素分析 |
| Related factors of postoperative pathologically confirmed stage N1-2 lymph node metastasis in patients with clinical stage N0 NSCLC |
| 投稿时间：2018-01-23 |
| DOI： |
| 中文关键词: 癌,非小细胞肺 淋巴结转移 危险因素 |
| 英文关键词: Carcinoma,non-small cell lung Lymph node metastasis Risk factor |
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| 中文摘要: |
| 目的 探讨临床N0期非小细胞肺癌(NSCLC)病人术后病理检查为N1-2期淋巴结转移的相关因素。方法 回顾性分析2011年1月至2017年12月三门峡市中心医院行解剖性肺叶切除+系统性淋巴结清扫治疗的T1aN0M0期NSCLC病人270例病例资料,统计术后病理确诊为淋巴结转移的比例,通过单因素和多因素分析N1-2期淋巴结转移的危险因素。结果 270例病人中,术后病理证实,32例出现N1-2期淋巴结转移,占11.85%。性别、年龄及吸烟与N1-2期淋巴结转移情况无统计学关联(P＞0.05),肿瘤直径、病理分型、癌胚胎抗原(CEA)肿瘤部位、病变位置与N1-2期淋巴结转移有统计学关联P＜0.05)；logistic多因素分析结果显示,肿瘤直径1[KG-*3]～2 cm、浸润性微乳头状癌(IMPC)、CEA＞5 μg/L水平是临床N0期NSCLC病人出现N1-2期淋巴结转移的独立危险因素。结论 T1aN0M0期NSCLC病人可能出现淋巴结转移,与肿瘤直径、IMPC、CEA水平有关。 |
| 英文摘要: |
| Objective To explore the related factors of postoperative pathologically confirmed stage N1-2 lymph node metastasis in patients with clinical stage N0 non-small cell lung cancer (NSCLC).Methods The clinical data of 270 patients with stage T1aN0M0 NSCLC who underwent anatomical lobectomy and systemic lymph node dissection in Sanmenxia Central Hospital from January 2011 to December 2017 were analyzed retrospectively.The proportion of lymph node metastases confirmed by pathology was statistically analyzed.The risk factors for stage N1-2 lymph node metastasis were analyzed by univariate and multivariate analysis.Results Of the 270 cases,postoperative pathology confirmed that 32 cases had stage N1-2 lymph node metastases,accounting for 11.85%.Gender,age and smoking were not related to stage N1-2 lymph node metastasis (P>0.05).The length diameter of tumors,pathological type,carcinoembryonic antigen (CEA) level,tumor location and lesion location were related to stage N1-2 lymph node metastasis (P＜0.05).Logistic multivariate analysis showed that the diameter of tumor of 1[KG-*3]～2 cm,invasive micropapillary carcinoma (IMPC) and CEA level>5 μg/L were independent risk factors for stage N1-2 lymph node metastasis in patients with NSCLC.Conclusion There may exist lymph node metastasis in patients with stage T1aN0M0 NSCLC,which is related to the diameter of tumor,IMPC and the CEA level. |
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