文章摘要
胡咏梅,夏小凤,马子凤,等.心理干预对输卵管性不孕病人心理健康及体外受精胚胎移植临床结局的影响[J].安徽医药,2019,23(8):1547-1549.
心理干预对输卵管性不孕病人心理健康及体外受精胚胎移植临床结局的影响
Influence of psychological intervention onmental health and clinical outcomes of tubal infertile patients in vitro fertilization-embryo transfer
投稿时间:2018-03-09  
DOI:
中文关键词: 不育,女(雌)性  输卵管阻塞  体外受精  胚胎移植  心理疗法  妊娠结局
英文关键词: Infertility,female  Fallopian tube obstrustion  Fertilization in vitro  Embryo transfer  Psychotherapy  Pregnancy outcome
基金项目:
作者单位
胡咏梅 解放军联勤保障部队第九〇一医院生殖中心,安徽 合肥 230031 
夏小凤 解放军联勤保障部队第九〇一医院生殖中心,安徽 合肥 230031 
马子凤 解放军联勤保障部队第九〇一医院生殖中心,安徽 合肥 230031 
姜宏 解放军联勤保障部队第九〇一医院生殖中心,安徽 合肥 230031 
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中文摘要:
      目的 探讨心理干预对输卵管性不孕病人心理健康及体外受精胚胎移植(IVF-ET)临床妊娠结局的影响。方法 选取2015年1月至2016年12月解放军联勤保障部队第九〇一医院416例因单一输卵管因素行IVF-ET的不孕病人,按病人就诊时间分为心理干预组(253例)和对照组(163例),对照组行常规护理,心理干预组在IVF-ET治疗全程中采用信息知识信念行为(IKAP)模式对夫妻双方进行针对性心理干预,比较心理干预组与对照组对病人心理健康及体外受精胚胎移植妊娠结局的影响。结果 两组病人年龄、不孕年限、体质指数(BMI)、基础卵泡刺激素(FSH)、内膜厚度均差异无统计学意义(P>0.05);干预后心理干预组SAS评分(29.81±4.46)分、SDS评分(23.74±3.71)分显著低于干预前(47.69±8.70)分、(44.11±6.43)分,均P=0.00;与对照组比,心理干预组促性腺激素(Gn)天数、获卵数、受精率、卵裂率、种植率、D3优胚率及临床妊娠率差异无统计学意义(P>0.05),Gn总量显著降低(2 231.86±696.98比2 396.86±742.15,P=0.02)。结论 对因单一输卵管因素行IVF-ET的不孕病人进行心理干预,能够显著改善病人心理健康状况,降低用药总量,对临床妊娠结局有改善趋势。
英文摘要:
      Objective To explore the influence of psychological intervention on mental health and clinical outcomes of tubal infertile patients in vitro fertilization-embryo transfer (IVF-ET).Methods 416 tubal infertile patients in 901 Hospital of PLA from January 2015 to December 2016 were randomly divided into psychological intervention group (n=253) and control group (n=163).Information-knowledge-attitude-practice intervention model (IKAP model) was given to the patients in psychological intervention group,meanwhile the patients in control group received conventional nursing.Then mental health evaluation and the pregnancy outcomes were compared between the two groups.Results There were no significant difference in age,infertility time,body mass index (BMI),basal FSH,and endometrial thickness between the two groups (P>0.05).The scores of SAS (47.69±8.70) and SDS (44.11±6.43) before intervention were significantly higher than that of post intervention (29.81±4.46,3.74±3.71) (P=0.00).Compared with the control group,Gn days,number of oocytes,fertilization rate,cleavage rate,implantation rate,high quality embryo rate of D3 and clinical pregnancy rate were not significantly different (P>0.05) in the intervention group,but the total dosage of Gn was significantly reduced (2 231.86±696.98 vs.2 396.86±742.15,P=0.02).Conclusion Psychological intervention for infertile patients with single tubal factor undergoing IVF-ET can significantly improve the mental health status of patients and reduce the total dosage of Gn,and ameliorate the clinical pregnancy outcome.
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