| 方映雪,夏修三,张凤琴,等.多重耐药鲍曼不动杆菌感染64例病原学特点、耐药情况及危险因素分析[J].安徽医药,2019,23(8):1689-1692. |
| 多重耐药鲍曼不动杆菌感染64例病原学特点、耐药情况及危险因素分析 |
| Etiologicfeature,drug resistance and the risk factors of 64 cases of multi-drug resistant acinetobacter baumanii infection |
| 投稿时间：2018-08-20 |
| DOI： |
| 中文关键词: 鲍氏不动杆菌 抗药性,多药 纸片扩散抗菌试验 危险因素 |
| 英文关键词: Acinetobacter baumanii Drug resistance,multiple Disk diffusion antimicrobial tests Risk factorsc |
| 基金项目: |
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| 摘要点击次数: 2026 |
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| 中文摘要: |
| 目的 了解多重耐药鲍曼不动杆菌感染的病原学特点、耐药性及其感染相关危险因素,为基层医院防控鲍曼不动杆菌的感染提供参考。方法 统计分析2016年6月至2018年7月庐江县人民医院64例多重耐药鲍曼不动杆菌和70例一般鲍曼不动杆菌感染病人的基本信息、住院治疗情况、药敏资料等数据。结果 64例多重耐药鲍曼不动杆菌感染病人所患基础疾病主要为颅脑损伤及老年慢性疾病(心、肺、脑血管),恶性肿瘤也占一定比例；标本主要来源为痰液(占96.88％)；病人分布科室按构成比从高到低排列依次为ICU、神经外科、呼吸内科；病人病原学标本耐药性监测从低到高依次为头孢哌酮/舒巴坦、阿米卡星,其他药物的耐药率均大于77.19％；危险因素分析显示:侵入性操作是多重耐药鲍曼不动杆菌感染发生的最主要危险因素。结论 危重症及老年慢性病并发呼吸系统感染病人是多重耐药鲍曼不动杆菌感染的重点人群；耐药率高；侵袭性操作、昏迷以及广谱抗菌药物应用是多重耐药鲍曼不动杆菌感染的危险因素。 |
| 英文摘要: |
| Objective To comprehend the etiologic feature,drug resistance,and the risk factors of acinetobacter baumanii infection,and to provide theoretical references for prevention and treatment of acinetobacter baumanii in primary hospital.Methods Basic information,inpatient treatment and drug sensitivity data of 64 cases of multidrug-resistant acinetobacter baumanii infection and 70 cases of general acinetobacter baumanii infection admiitted to Lujiang County People's Hospital from June 2016 to July 2018 were analyzed.ResultsThe basic diseases of 64 patients with multidrug-resistant acinetobacter baumannii infection were mainly chronic disease (heart,lung,and brain vessels) and craniocerebral injury in the elderly,and malignant tumors also accounted for a certain proportion.Most of the acinetobacter baumanii were from sputa (96.88%).Patients were distributed in ICU,the Department of Neurosurgery and the Department of Respiratory Medicine,in order of composition ratio from high to low.The pathogenic specimens of these patients were Cefoperazone and Sulbactam,followed by Amikacin,from higher drug resistance to lower drug resistance while the drug resistance rate of other drugs all exceeded 77.19%.The analysis of risk factors indicated that invasive operation was one of the main risk factors that resulted in the infections of acinetobacter baumanii.Conclusion The key crowd of the infections of acinetobacter baumanii are patients with critical disease and old chronic respiratory disease.The risk factors include high drug resistance rate,invasive operation,coma,and application of broad spectrum antibiotics. |
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