| 罗志红,李新贵,陈慧颖,等.临床药师干预提升碳青霉烯类抗菌药物合理使用效果分析[J].安徽医药,2019,23(10):2098-2100. |
| 临床药师干预提升碳青霉烯类抗菌药物合理使用效果分析 |
| Effect analysis of rational use of carbapenems antibiotics by clinical pharmacist intervention |
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| DOI：10.3969/j.issn.1009?6469.2019.10.049 |
| 中文关键词: 药学服务 药物处方 临床药师 药学干预 碳青霉烯类抗菌药物 效果分析 |
| 英文关键词: Pharmaceutical services Drug prescriptions Clinical pharmacist Pharmaceutical intervention Carbapenemsantimicrobial Effect analysis |
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| 中文摘要: |
| 目的探析临床药师干预碳青霉烯类抗菌药物合理使用效果。方法采用安徽省儿童医院美康临床药学管理系统生成随机数的方法随机抽取 2017年 8—12月(干预前)与 2018年 8—12月(干预后)使用碳青霉烯类抗菌药物的住院病例各 100例，进行合理性分析。结果临床药师干预后，该院碳青霉烯类抗菌药物使用评价得分由( 74.45±7.26)分升高到( 94.70±5.31)分；适应证合理率由 86%提高到 98%；品种选择合理率由 87%提高到 99%；单次剂量、溶液及配伍合理率由 65%提高到 98%；药敏送检率由 78%提高到 95%；申请会诊单由 72%提高到 100%；出院病儿碳青霉烯类抗菌药物使用强度由干预前( 3.96±0.86) DDDs·(100人) -1·d-1降到( 2.27±0.72)DDDs·(100人) -1·d-1。均差异有统计学意义( P＜0.05)。结论临床药师干预显著提高碳青霉烯类抗菌药物合理使用率，规范临床碳青霉烯类抗菌药物的应用情况，进一步促进临床合理用药。 |
| 英文摘要: |
| Objective To explore the effect of clinical pharmacists’intervention on the rational use of carbapenems. Methods One hundred hospitalized cases treated with carbapenems from August to December 2017(before the intervention)and August to December 2018(after the intervention)in Meikang clinical pharmacy management system in Anhui Children's Hospital were ran? domly selected and analyzed. Results After intervention by clinical pharmacists，evaluation score of carbapenems antibacterial drugs increased from(74.45±7.26)to(94.70±5.31)； the rational rate of indication increased from 86% to 98%；the rational rate of variety selection increased from 87% to 99%；the rational rate of single dose，solution and compatibility increased from 65% to 98%；the rate of drug susceptibility test was increased from 78% to 95%，the single consultation rate increased from 72% to 100%； application intensity of carbapenems in children with the hospital decreased from(3.96±0.86) DDDs·(100 children)-1 ·d-1 to |
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