文章摘要
焦晨阳,王凯,钱鹏,等.结直肠侧向发育型肿瘤内镜诊治分析[J].安徽医药,2019,23(11):2203-2206.
结直肠侧向发育型肿瘤内镜诊治分析
Analysis of endoscopic therapy for colorectal laterally spreading tumor
  
DOI:10.3969/j.issn.1009?6469.2019.11.021
中文关键词: 结直肠肿瘤  侧向发育型肿瘤  内镜黏膜下剥离术  内镜黏膜切除术
英文关键词: Colorectal neoplasms  Colorectal laterally spreading tumors  Endoscopic submucosal dissection  Endoscopic mu? cosal resection
基金项目:
作者单位E-mail
焦晨阳 泰州市人民医院消化科江苏泰州 225300  
王凯 泰州市人民医院消化科江苏泰州 225300  
钱鹏 泰州市人民医院消化科江苏泰州 225300  
杨斌 泰州市人民医院消化科江苏泰州 225300  
伏亦伟 泰州市人民医院消化科江苏泰州 225300 yiweifu@sina.com 
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中文摘要:
      目的探讨结直肠侧向发育型腺瘤( LST)的临床、内镜及病理特征,以及相关治疗方法的安全性及有效性。方法回顾性收集 2015年 8月至 2018年 4月于泰州市人民医院行内镜下治疗的 103例 LST病人的相关资料,统计 LST病人的临床表现、内镜特征、治疗方法、术后病理及其并发症,按内镜下形态分成颗粒均一型、结节混合型、扁平隆起型、假凹陷型,比较四种类型 LST的病灶大小、病理特征。结果 103例病人的 104处病变纳入本研究, 104处病变中颗粒均一型 19处(占 18.3%)结节混合型 27处(占 26.0%)扁平隆起型 45处( 43.2%)假凹陷型 13处( 12.5%)。四种类型 LST直径的中位数分别为 30、30、15、2,5 mm,其中扁平隆起性和假,凹陷型直径差异有统计学意,义( P<0.05)。扁平隆起型和假凹陷型高级别上皮内瘤变发生率差异有统计学意义( P<0.05)。其余病理类型发生率各亚型间差异无统计学意义。 104处 LST中 51例行 ESD,53例行 EMR,整块切除率 100%。ESD治疗病人中 1例术中出血, 1例穿孔; EMR组 1例术后第 4天出血。术后 95例随访成功,其中 1例复发。结论 ESD和 EMR在 LST的治疗上有着较高的有效性和安全性。
英文摘要:
      Objective To explore the clinical,endoscopic,pathological features of colorectal laterally spreading tumors(LST)and assess the safety and effectiveness of relevant endoscopic therapy.Methods We retrospectively collected relevant datum of 103 pa? tients underwent endoscopic therapy in Taizhou People’s Hospital during August 2015 and April 2018.All the LSTs were classi? fied into four subtypes,including homogeneous granular,nodular mixed,flat elevated and pseudo?depressed types.We compared clin?icopathological datum and therapy parameters between the four subtypes.Results A total of 104 lesions of 103patients were in? cluded.Among the 104 lesions,homogeneous granular,nodular mixed,flat elevated and pseudo?depressed types were 19 cases(18.3%)27 cases(26.0%)45 cases(43.2%)13 cases(12.5%),respectively.Median diameter of each subtype was 30,30,15,25 mm.Thedif,ferenceofdiameter,betweenflateleva,ted and pseudo?depressed types was statistically significant(P<0.05).The most common pathological type was high?grade intraepithelial neoplasia(HGIN).The percentage of HGIN of flat elevated and pseudo?de? pressed types was statistically significant(P<0.05).Other pathological types didn’t differ among subtypes.There were 51 lesions
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