文章摘要
苏慧霞,陈艳,杨欣.早期促醒康复干预对重症病毒性脑炎伴植物状态病儿临床预后的影响[J].安徽医药,2020,24(1):20-23.
早期促醒康复干预对重症病毒性脑炎伴植物状态病儿临床预后的影响
Influence of early awakening rehabilitation intervention on clinical prognosis of children with severe viral encephalitis accompanied by vegetative state
  
DOI:10.3969/j.issn.1009?6469.2020.01.006
中文关键词: 脑炎,病毒性  持续植物人状态  诱发电位  脑电描记术  电刺激疗法  运动疗法  音乐疗法  认知疗法  治疗结果  康复  儿童  早期促醒
英文关键词: Encephalitis,viral  Persistent vegetative state  Evoked potentials  Electroencephalography  Electric stimulation therapy  Exercise therapy  Music therapy  Cognitive therapy  Treatment outcome  Rehabilitation  Child  Early awakening
基金项目:
作者单位
苏慧霞 榆林市儿童医院儿内二科陕西榆林 719000 
陈艳 榆林市儿童医院重症医学科陕西榆林 719000 
杨欣 榆林市儿童医院重症医学科陕西榆林 719000 
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中文摘要:
      目的探讨早期促醒康复干预对重症病毒性脑炎伴植物状态病儿临床预后的影响。方法选取陕西省榆林市儿童医 2014年 8月至 2017年 12月收治重症病毒性脑炎伴植物状态病儿共 127例,其中生命体征稳定出院但机体功能 4周内未完全恢复、后再行促醒康复干预共 71例设为对照组,生命体征稳定后直接行促醒康复干预共 56例设为观察组,比较两组治疗前后植物状态分级、植物状态评分、脑电图评分、脑干诱发电位评分、随访 GFMF评分及随访韦氏评分。结果观察组治疗后 1个月、 3个月植物状态评分[(473.71±70.16)分,(523.70±61.26)分]、脑电图评分[(4.51±1.10)分,(4.93±1.36)分]及脑干诱发电位评分[(4.93±1.36)分,(3.80±1.02)分]均显著高于治疗后对照组[(3.60±0.81)分,(1.32±0.40)分];[(4.05±0.94)分,(2.41±0.67)分];[(4.20±1.01)分,(3.12±0.85)分]、治疗前观察组[(326.53±30.34)分,(473.71±70.16)分,(523.70±61.26)分](P<0.05);同时观察组随访 3个月、 9个月的 GFMF评分[(6.75±1.38)分,(78.59±6.50)分]和韦氏评分[(51.43±5.90)分,(98.63±16.28)分]均显著高于对照组[(6.08±1.44)分,(62.43±5.06)分;(48.38±5.67)分,(85.06±12.05)分](P<0.05)。结论早期促醒康复干预用于重症病毒性脑炎伴植物状态病儿可有效改善意识状态,提高肢体活动功能,并有助于促进认知水平恢复。
英文摘要:
      Objective To investigate the influence of early awakening rehabilitation intervention on clinical prognosis of childrenwith severe viral encephalitis accompanied by vegetative state.Methods 127 children with severe viral encephalitis accompanied by vegetative state were chosen in Yulin children??s Hospital of Shaanxi in the period from Auguste 2014 to December 2017 and di? vided into two groups including control group(71 children)with awakening rehabilitation intervention which discharged with sta?ble vital signs while incomplete recovery within 4 weeks and observation group(56 children)with early awakening rehabilitation interventiondirectly after stable vital signs.The vegetation status grading,vegetation status score,electroencephalogram score and brainstem evoked potential score before and after treatment,GFMF score and Wechsler score with follow?up of both groups were compared.Results The vegetation status grading of obseruation group after treatment were significant better than control group and before treatment(P<0.05).The plant status score[( 473.71±70.16)points,(523.70±61.26)points], electroencephalogram score[(4.51±1.10)points,(4.93±1.36)points]and brainstem evoked potential score[(4.93±1.36)points,(3.80±1.02)points]of observa? tion group after treatment were significant more than control group after treatment[(3.60±0.81)points,(1.32±0.40)points];[(4.05±0.94)points,(2.41±0.67)points];[(4.20±1.01)points,(3.12±0.85)points]and observation group before treatment[(326.53±30.34) points,(473.71±70.16)points,(523.70±61.26)points](P<0.05).The GFMF score and Wechsler score with follow?up of observationgroup with follow?up were significant higher than control group[( 6.08±1.44)points,(62.43±5.06)points;(48.38±5.67)points,(85.06±12.05)points](P<0.05).Conclusion Early awakening rehabilitation intervention in the treatment of children with severeviral encephalitis accompanied by vegetative state can efficiently improve the consciousness state,higher the limb movement func? tion and promote the recovery of cognitive level.
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