| 张占华,张念杰,梁敏,等.腹腔镜手术对胃癌病人临床指标及创伤应激指标的影响[J].安徽医药,2020,24(4):779-782. |
| 腹腔镜手术对胃癌病人临床指标及创伤应激指标的影响 |
| Effects of laparoscopic surgery on clinical indexes and traumatic stress indexes in patients with gastric cancer |
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| DOI：10.3969/j.issn.1009?6469.2020.04.036 |
| 中文关键词: 胃肿瘤 胃切除术 内窥镜检查，胃肠道 氧化性应激 住院时间 C反应蛋白质 一氧化氮 白细胞介素 6 内皮素 临床指标 |
| 英文关键词: Stomach neoplasma Gastrectomy Endoscopy,gastrointestinal Oxidative stress Hospital stay C?reactive protein Nitric oxide Interleukin?6 Endothelin Clinical index daysafteroperationweresignific, |
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| 中文摘要: |
| 目的探讨腹腔镜手术对胃癌病人临床指标及创伤应激指标的影响。方法选择三河市燕郊人民医院于 2016年 1月至 2017年 12月行腹腔镜下胃癌根治术的病人 40例为试验组。选择该院 2014年 1月至 2015年 12月行开腹胃癌根治术的 40例病人为对照组。比较两组手术情况、创伤应激指标变化情况。结果试验组手术用时长于对照组，差异有统计学意义( P＜0.05)；试验组和对照组清扫淋巴结数量对比，差异无统计学意义( P＞0.05)；试验组和对照组切口长度分别为( 6.34±1.10)cm、(19.32±2.25)cm，术中出血量为( 212.21±46.43)mL、(362.51±61.65)mL，术后肛门排气时间为( 2.67±1.10)d、(4.31±1.42)d，首次流质饮食时间为( 5.36±1.88)d、(7.25±2.14)d，住院时间为( 9.38±2.86)d、(12.09±3.24)d，差异有统计学意义( P＜0.05)；术后 5d试验组血清内皮素( ET)、 C?反应蛋白( CRP)、一氧化氮( NO)、白细胞介素 ?6(IL?6)水平均低于对照组，差异有统计学意义( P＜0.05)。结论与开腹手术相比，腹腔镜手术具有创伤小、术后恢复快，创伤应激程度更低等优势。 |
| 英文摘要: |
| Objective To explore the clinical effects of laparoscopic surgery on clinical indexes and traumatic stress indexes in pa?tients with gastric cancer.Methods Forty patients who had undergone laparoscopic radical gastrectomy for gastric cancer in Yanji? ao People’s Hospital between January 2016 and December 2017 were selected as the experimental group，and another 40 patientswho had received open radical gastrectomy in the same hospital between January 2014 and December 2015 were set as the controlgroup.The surgical results and the changes of traumatic stress index were compared between the two groups.Results The operation duration in the experimental group was shown to be longer than that in the control group，with statistically significant difference be? tween the two groups(P＜0.05).There was no significant difference in the number of lymph nodes cleared between the experimental group and the control group(P＞0.05).The incision lengths，intraoperative bleeding volume，the time for the first anal evacuation， the first time for liquid dietary intake，and the length of hospital stay in the experimental group and the control group were(6.34±1.10)cm vs.(19.32±2.25)cm(212.21±46.43)mL vs.(362.51±61.65)mL，(2.67±1.10)d vs.(4.31±1.42)d，(5.36±1.88)d vs.(7.25± 2.14)d，and(9.38±2.86)d vs.(12.09±3.24)d，respectively，with all the differences shown to be statistically significant(P＜0.05). The levels of endothelin(ET)C?reactive protein(CRP)，nitric oxide(NO)and interleukin?6(IL?6)in the experimental group at 5 antly lower than those in the control group(P＜0.05).Conclusion Compared with open surgery， laparoscopic surgery has the advantages of smaller trauma，rapid recovery after operation and lower degree of traumatic stress. |
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