| 笪伟,张泓.毛细血管充盈时间预测脓毒性休克病人预后的价值[J].安徽医药,2020,24(6):1171-1173. |
| 毛细血管充盈时间预测脓毒性休克病人预后的价值 |
| Significance of capillary re?ll time in predicting prognosis of septic shock |
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| DOI：10.3969/j.issn.1009?6469.2020.06.027 |
| 中文关键词: 休克，脓毒性 毛细血管充盈时间 乳酸 血压 微循环 预后 |
| 英文关键词: Shock,sepsis Capillary re?ll time Lactic acid Blood pressure Microcirculation Prognosis |
| 基金项目: |
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| 摘要点击次数: 1968 |
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| 中文摘要: |
| 目的评估皮肤毛细血管充盈时间( CRT)在脓毒性休克病人中的应用价值。方法 2016年 5月至 2019年 5月安徽医科大学第一附属医院收治的脓毒性休克 73例，根据脓毒性休克病人 28 d转归分为存活组( 35例)与死亡组( 38例)，采用非参数检验比较两组病人 CRT，通过受试者工作特征曲线( ROC)分析 CRT预测脓毒性休克病人预后的阈值及其灵敏度与特异度等诊断试验评价指标。结果死亡组 CRT明显高于存活组［ 5.50(4.40，5.90)s比 2.20(1.90，2.80)s，P＜0.05］。 ROC曲线下面积(AUC)显示: AUC＝0.83，最佳截断值为 2.4 s时预测脓毒性休克病人死亡，灵敏度高达 94%，特异度为 84%。结论脓毒性休克 6h液体复苏后 CRT可以预测脓毒性休克病人的预后。 |
| 英文摘要: |
| Objective To evaluate the application value of skin capillary filling time(CRT)in patients with septic shock.Meth? ods Seventy?three cases of patients with septic shock in Departments of Emergency，The First Affiliated Hospital of Anhui Medi?cal University from May 2016 to May 2019 were selected and assigned into survival group(35 cases)and death group(38 cases) according to 28 days outcome in patients with septic shock.Nonparametric test was used to compare two groups of patients with cap?illary re?ll time(CRT)，the ROC curve analysis of the CRT was used to predict the prognosis of patients with septic shock thresh?old and its degree of sensitivity and specific diagnostic test evaluation index.Results The CRT of death group was obviously high? er than that of survival group，and the difference was statistically significant［5.50(4.40，5.90)s vs. 2.20(1.90，2.80)s，P＜0.05］. The area under curve(AUC)of ROC showed that AUC was 0.83，and the best cut?off value was 2.4 s to predict the death of pa? tients with septic shock，with a sensitivity of 94% and a speci?city of 84%.Conclusion After 6 hours of fluid resuscitation，CRT can predict the prognosis of the patients with septic shock. |
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