| 宋耕,杨震.肝脏广泛转移癌调强放疗 10例近期疗效观察[J].安徽医药,2020,24(7):1385-1387. |
| 肝脏广泛转移癌调强放疗 10例近期疗效观察 |
| The short?term efficacy of intensity modulated radiation therapy in 10 patients with diffuse liver metastases |
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| DOI：10.3969/j.issn.1009?6469.2020.07.029 |
| 中文关键词: 肝肿瘤/放射疗法 肿瘤转移 放射疗法，调强适形 |
| 英文关键词: Liver neoplasms/radiotherapy Neoplasm metastasis Radiotherapy,intensity?modulated |
| 基金项目: |
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| 摘要点击次数: 1995 |
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| 中文摘要: |
| 目的观察肝脏广泛转移癌调强放疗的近期疗效和不良反应。方法收集 2016年 1月至 2018年 2月于安徽医科大学第二附属医院接受调强放疗的 10例肝脏广泛转移癌病人，放疗剂量 22～50 Gy，单次分割剂量 1.8～2.0 Gy，评价疗效及副反应。结果 7例腹痛症状缓解。 7例可进行疗效评价:部分缓解 2例，疾病稳定 5例，中位无进展生存期为 3个月( 2～18个月)。副反应多为轻中度的中性粒细胞减少、肝功能损害和消化道反应，只有 1例因肝性脑病而停止放疗。结论调强放疗治疗肝脏广泛性转移癌安全有效。 |
| 英文摘要: |
| Objective To evaluate the short?term efficacy and toxic effects of intensity modulated radiation therapy(IMRT)for pa? tients with diffuse liver metastases.Methods From January 2016 to February 2018，10 patients with diffuse liver metastases admit?ted to The Second Affiliated Hospital of Anhui Medical University were treated with IMRT.The dose ranged from 22 Gy to 50 Gyand the doses per fraction was 1.8～2 Gy.The efficacy and adverse effects were accessed.Results The abdominal pain relieved by radiotherapy in 7 patients.Among 7 evaluable patients，there were 2 cases of partial response，5 cases of stable disease.The medi? an progress free survival was 3 months(ranged 2～18 months).The radiotherapy related toxicities were mild to moderate neutro? penia，hepatic dysfunction and response of digestive tract.Only one patient discontinued therapy due to hepatic encephalopathy.Conclusion IMRT was effective and safe in managing diffuse liver metastases. |
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