文章摘要
胡晗宇,艾芳,刘玲艳,等.三维能量多普勒超声在定量评估生长受限胎儿肾脏血流量中的应用[J].安徽医药,2020,24(8):1577-1581.
三维能量多普勒超声在定量评估生长受限胎儿肾脏血流量中的应用
Application of quantitative three?dimensional power doppler sonography for assessment of the fetal renal blood flow in fetuses with growth restriction
  
DOI:10.3969/j.issn.1009?6469.2020.08.025
中文关键词: 胎儿生长迟缓  超声检查,产前  胎儿  肾脏  定量分析
英文关键词: Fetal growth retardation  Ultrasonography,prenatal  Fetus  Kidney  Quantitative analysis
基金项目:
作者单位E-mail
胡晗宇 云南省第一人民医院、昆明理工大学附属医院妇产科云南昆明650032  
艾芳 云南省第一人民医院、昆明理工大学附属医院妇产科云南昆明650032  
刘玲艳 云南省第一人民医院、昆明理工大学附属医院妇产科云南昆明650032  
董旭东 云南省第一人民医院、昆明理工大学附属医院妇产科云南昆明650032 wandashiji12@163.com 
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中文摘要:
      目的探讨三维能量多普勒超声定量评估生长受限胎儿(fetuses with fetal growth restriction,FGR)和正常胎儿的肾脏血流灌注的价值。方法选取云南省第一人民医院 2017年 5月至 2018年 10月孕期妇女为研究对象,应用三维能量多普勒超声定量分析孕 20~40周单胎 FGR和正常胎儿的肾脏血管化指数(vascularization index,VI)、血流指数(flow index,FI)、血管化 ?血流指数(vascularization?flow index,VFI)。记录并比较两组胎儿 VI、FI、VFI之间的差异,以孕周为自变量,分别进行线性回归分析,得到回归模型。结果共纳入 41例正常胎儿和 32例 FGR胎儿。 FGR胎儿与正常胎儿 20周、 24周、 28周的 VI、FI、VFI比较差异无统计学意义, 32周[FGR胎儿 VI(2.88±0.46)比正常胎儿 VI(3.16±0.53)][FGR胎儿 FI(44.62±0.97)比正常胎儿 FI(45.74±0.83)][FGR胎儿 VFI(1.23±0.24)比正常胎儿 VFI(1.44±0.08)]、 36周[FGR胎儿 VI(3.59±0.44)比正常胎儿 VI(3.82±0.22)][FGR胎儿 FI(44.64±0.72)比正常胎儿 FI(47.18±0.49)][FGR胎儿 VFI(1.54±0.18)比正常胎儿 VFI(1.81±0.07)]、 40周[FGR胎儿 VI(3.63±0.77)比正常胎儿 VI(5.40±0.15)][FGR胎儿 FI(44.85±0.59)比正常胎儿 FI(47.97±0.58)][FGR胎儿 VFI(1.36±0.38)比正常胎儿 VFI(2.38±0.41)]比较,差异有统计学意义(P<0.05); FGR胎儿 VI、FI、VFI与孕周(GA)的最佳拟合方程分别为: VIFGR=0.1494GA?2.001(R2=0.8210)、 FIFGR=0.1587GA+39.07(R2=0.5205)、 VFIFGR=0.05677GA-0.6741(R2=0.9173)。结论三维能量多普勒超声测量的胎儿肾 VI、FI、VFI在产前预测 FGR中有一定的价值。
英文摘要:
      Objective To investigate the value of quantitative three?dimensional energy doppler ultrasound for assessment of the fe?tal renal blood flow in fetuses with growth restriction(FGR)and normal fetuses.Methods The pregnant women in The First Peo? ple’s Hospital of Yunnan Province from May 2017 to October 2018 were selected as the research objects.Three?dimensional energydoppler ultrasound was used to quantitatively analyze the renal vascularization index(VI),flow index(FI),and vascularization? flow index(VFI)of a single fetus at 20?40 weeks pregnant with FGR and normal fetus.The differences of VI,FI and VFI of the two groups were recorded and compared.The gestational week was taken as the independent variable,and linear regression analysis was carried out to obtain the regression model.Results A total of 41 normal fetuses and 32 FGR fetuses were included.There was no statistically significant difference in VI,FI and VFI between FGR fetus and normal fetus at 20 weeks,24 weeks and 28 weeks. However,there was statistically significant difference between FGR fetus and normal fetus at 32 weeks[FGR fetus VI(2.88±0.46) vs. normal fetus VI(3.16±0.53)][FGR fetus FI(44.62±0.97)vs. normal fetus FI(45.74±0.83)][FGR fetus VFI(1.23±0.24)vs. normal fetus VFI(1.44±0.08)]36 weeks[FGR fetus VI(3.59±0.44)vs. normal fetus VI(3.82±0.22)][FGR fetus FI(44.64±0.72) vs. normal fetus FI(47.18±0.49),][FGR fetus VFI(1.54±0.18)vs. normal fetus VFI(1.81±0.07)]40 weeks[FGR fetus VI(3.63±0.77)vs. normal fetus VI(5.40±0.15)][FGR fetus FI(44.85±0.59)vs. normal fetus FI(47.97±0.58][FGR fetus VFI(1.36±0.38) vs. normal fetus VFI(2.38±0.41)](P<0.05).The optimal fitting equations for VI,FI,VFI and gestational age(GA)were VIFGR=0.1494 ga?2.001(R2=0.8210),FIFGR=0.1587GA+39.07(R2=0.5205),and VFIFGR=0.05677GA-0.6741(R2=0.9173),respective? ly.Conclusion The VI,FI and VFI of fetal kidney measured by three?dimensional energy doppler ultrasound have definite value in prenatal detection FGR.
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