| 朱莉,王婧,章宏毅.三氧化矿物聚合体联合富血小板纤维蛋白在显微根尖手术治疗慢性根尖周炎中的疗效观察[J].安徽医药,2020,24(8):1596-1599. |
| 三氧化矿物聚合体联合富血小板纤维蛋白在显微根尖手术治疗慢性根尖周炎中的疗效观察 |
| Effect of mineral trioxide aggregate combined with platelet?rich fibrin in microapical surgery for chronic periapical periodontitis |
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| DOI：10.3969/j.issn.1009?6469.2020.08.030 |
| 中文关键词: 根尖周炎 富血小板血浆 根尖切除术 根管充填 三氧化矿物聚合体 显微根尖手术 |
| 英文关键词: Pariapical periodontitis Platelet?rich plasma Apicoectomy Root canal obturation Mineral trioxide aggregate Apical microsurgery |
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| 中文摘要: |
| 目的评价三氧化矿物聚合体(Mineral trioxide aggregate，MTA)联合富血小板纤维蛋白(Platelet?rich fibrin，PRF)在显微根尖手术治疗慢性根尖周炎中的作用。方法选取 2015年 11月至 2017年 10月荆州市第一人民医院慢性根尖周炎病人 42例，共 60颗牙，均进行显微根尖手术，包括根尖切除、根尖倒预备和 MTA倒充填。采用随机数字表法分成两组，对照组完成 MTA倒充填后直接缝合，观察组完成 MTA倒充填后将制备的 PRF碎片填塞至根尖区骨腔内，并盖上 PRF膜再缝合。手术后即刻及术后 48 h行疼痛视觉模拟(VAS)评分，比较两组疼痛反应程度变化。术后 3个月、 6个月复查，评估临床检查指标及根尖 X线片，分析手术成功率及根尖区骨密度变化。结果 60颗患牙中疗效判定成功的患牙为 53颗，成功率 88.33%。观察组术后 48 h VAS减少值为(2.39±0.73)分，对照组为(1.30±0.58)分，差异有统计学意义(P＜0.01)。术后 3个月观察组 X线片根尖区牙槽骨平均灰度值较术前增加(48.37±14.24)对照组增加(30.38±11.72)两组间差异有统计学意义(P＜0.01)；术后 6个月观察组平均灰度值较术前增加(57.84±12.73)对照，组增加(58.32±13.15)，两组，差异无统计学意义(P＞0.05)。结论 MTA联合 PRF较单纯 MTA倒充填在显微根尖手术的手术，成功率、根尖区骨密度的远期变化方面均无明显改善，但在术后短期内有减轻手术疼痛反应及促进骨组织快速修复的作用。 |
| 英文摘要: |
| Objective To evaluate the effect of mineral trioxide aggregate(MTA)combined with platelet?rich fibrin(PRF)in mi? croapical surgery for chronic periapical periodontitis.Methods Forty?two patients with chronic periapical periodontitis，who under? went apical microsurgery in The First People’s Hospital of Jingzhou from November 2015 to October 2017，were enrolled in the study，including 60 teeth.The surgery included apical resection，apical preparation and MTA apical filling.The patients were random? ly assigned into two groups.In the control group，direct suture was performed after MTA apical filling，while in the study group，the prepared PRF fragments were filled into the scratched bone cavity in the apical region after filling，and then covered with PRF film before suturing.Visual analogue scale(VAS)scores were recorded immediately after operation and 48 hours after operation to com?pare the changes of pain response between the two groups.Clinical examination indicators and apical X ? rays were evaluated andthe success rate of operation and the bone mineral density(BMD)of the apical region were analyzed after 3 months and 6 months of operation.Results Fifty?three teeth were successfully treated，with a success rate of 88.33%.The VAS decreased by(2.39±0.73)at 48 hours in the study group and(1.30±0.58)at 48 hours in the control group.There was a significant difference in VAS between the two groups(P＜0.001).The average gray value of alveolar bone in apical region increased by(48.37±14.24)in the study group，and by(30.38±11.72)in the control group 3 months after operation；the difference was statistically significant(P＜0.01). |
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