| 张健,辛克锋,李劲松,等.脾脏硬度值、天冬氨酸氨基转移酶和血小板比率指数、 FIB?4指数对肝硬化食管静脉曲张的预测价值[J].安徽医药,2020,24(8):1613-1616. |
| 脾脏硬度值、天冬氨酸氨基转移酶和血小板比率指数、 FIB?4指数对肝硬化食管静脉曲张的预测价值 |
| Clinical value of SSM，APRI，and FIB?4 in predicting esophageal varices in patients with liver cirrhosis |
| |
| DOI：10.3969/j.issn.1009?6469.2020.08.035 |
| 中文关键词: 食管和胃静脉曲张/诊断 肝硬化 天冬氨酸氨基转移酶类 血小板 超声检查 瞬时弹性成像技术 |
| 英文关键词: Esophageal and gastric varices/diagnosis Liver cirrhosis Aspartate aminotransferases Blood platelets Ultraso? nography Elasticity imaging techniques |
| 基金项目: |
|
| 摘要点击次数: 2317 |
| 全文下载次数: 708 |
| 中文摘要: |
| 目的探讨脾脏硬度值(SSM)、天冬氨酸氨基转移酶和血小板比率指数(APRI)、 FIB?4指数在肝硬化食管静脉曲张(EV)无创诊断中的应用价值。方法选择 2016年 6月至 2018年 12月在阜阳市第二人民医院就诊的 105例肝硬化病人，均行胃镜检查、测量 SSM、检测肝功能及血常规等生化指标，应用受试者工作曲线评估 SSM、APRI、FIB?4预测肝硬化病人 EV程度的能力。结果 SSM、APRI及 FIB?4值均随 EV程度的加重而呈上升趋势，在不同程度 EV之间差异有统计学意义(P＜0.05)。 SSM、 APRI、FIB?4预测肝硬化 EV的 AUC值分别为 0.859、0.753、0.795，预测重度 EV的 AUC值分别为 0.833、0.788、0.801。结论 SSM、APRI及 FIB?4在预测肝硬化病人 EV是否存在及严重程度有较好的应用价值。 |
| 英文摘要: |
| Objective To explore the application value of spleen stiffness measurement(SSM)，aspartate aminotransferase?to?plate? let ratio index(APRI)and fibrosis 4 score(FIB?4)in noninvasive diagnosis of esophageal varices(EV)in patients with liver cir? rhosis.Methods One hundred and five patients with liver cirrhosis who received treatment in No.2 People’s Hospital of Fuyang City from June 2016 to December 2018 were chosen.The patients were all offered gastroscopy，SSM，liver function and blood routine examination.Receiver operating curve was taken to assess the capability of SSM，APRI，FIB?4 in predicting EV in patients with liv? er cirrhosis.Results Difference in SSM，APRI and FIB?4 value was of statistical significance among EV of different degrees(P＜0.05)and SSM，APRI and FIB?4 values tended to rise as EV degree aggravated.AUC values of SSM，APRI and FIB?4 in predicting EV of liver cirrhosis patients were 0.859，0.753 and 0.795 respectively.And AUC values in predicting severe EV were 0.833，0.788 and 0.801 respectively.Conclusion SSM，APRI and FIB?4 were of good application value in predicting EV existence in patients with liver cirrhosis and its severity. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
