| 戴冬艳,徐佳,蔡鹏.电感耦合等离子发射光谱法同时测定异甘草酸镁注射液中异甘草酸镁和氯化钠的含量[J].安徽医药,2021,25(1):28-31. |
| 电感耦合等离子发射光谱法同时测定异甘草酸镁注射液中异甘草酸镁和氯化钠的含量 |
| and sodium chloride in the magnesium glycyrrhizinate injection |
| |
| DOI：10.3969/j.issn.1009?6469.2021.01.007. |
| 中文关键词: 甘草酸 等离子气体 电感耦合等离子体发射光谱(ICP?OES) 回收率 异甘草酸镁注射液 氯化钠 含量测定 |
| 英文关键词: Glycyrrhizic acid Plasma gases Inductively coupled plasma atomic emission spectrometry(ICP?OES) Rate of recovery Magnesium glycyrrhizinate injection Sodium chloride Content determination |
| 基金项目: |
|
| 摘要点击次数: 1606 |
| 全文下载次数: 715 |
| 中文摘要: |
| 目的建立电感耦合等离子发射光谱(ICP?OES)法同时测定异甘草酸镁注射液中异甘草酸镁和氯化钠含量的新方法。方法 2018年 11月至 2019年 6月，采用 ICP?OES法直接测定供试品稀释液，镁、钠的发射谱线分别为 285.213、588.995 nm。结果镁离子、钠离子的线性范围分别为 0.5～10.0 μg/mL(r＝0.999 8)和 15～100 μg/mL(r＝0.999 2)；镁离子、钠离子的平均加样回收率分别为 96.73%、96.98%，RSD分别为 1.87%和 1.79%(n＝6)，3批样品 ICP?OES法测定的结果与按标检验结果没有显著差异。结论该方法灵敏度高、专属性强、结果准确、操作简便，具有多元素同时测定的特点，可同时测定异甘草酸镁注射液中异甘草酸镁和氯化钠的含量，用于异甘草酸镁注射液的质量控制。 |
| 英文摘要: |
| Objective To establish a new method for the simultaneous determination of the content of magnesium glycyrrhizinateand sodium chloride in the Magnesium glycyrrhizinate injection by inductively coupled plasma?atomic emission spectrometry(ICP? OES).Methods From November 2018 to June 2019，ICP?OES was used to measure the diluent of the tested products，and the emission lines of Mg2+ and Na+ were 285.213 and 588.995 nm，respectively.Results The linear ranges of Mg2+ and Na+ were 0.5～10.0μg/mL(r＝0.999 8)， 15～100 μg/mL(r＝0.999 2)， respectively.The average recoveries of Mg2+ and Na+ were 96.73%，96.98%(n＝6)，and RSDs were 1.87% and 1.79%(n＝6).The results of the three batches of sample showed that there were nosignificant difference between the ICP?OES method and the standard method.Conclusion This method has the characteristics of high sensitivity，strong speciality，high accuracy，simple operation，simultaneous determination of multiple elements，and can be used to determine the content of magnesium isoglycyrrhizinate and sodium chloride in Magnesium glycyrrhizinate injection. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
