| 张荣林,张巡江,刘洋,等.低浓度对比剂全脑三维数字减影血管造影用于动脉瘤检查[J].安徽医药,2021,25(10):2061-2064. |
| 低浓度对比剂全脑三维数字减影血管造影用于动脉瘤检查 |
| The application value of low-concentration contrast agent 3D-DSA cerebral angiography in patients with suspected aneurysms |
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| DOI：10.3969/j.issn.1009-6469.2021.10.035 |
| 中文关键词: 颅内动脉瘤 血管造影术，数字减影 造影剂 低浓度对比剂 图像质量 |
| 英文关键词: Intracranial aneurysm Angiography,digital subtraction Contrast media Low-concentration contrast agent Image quality |
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| 中文摘要: |
| 目的探究低浓度对比剂全脑三维数字减影血管造影( 3D-DSA)在动脉瘤病人检查中的应用价值。方法将 2018年 2月至 2019年 4月在宜宾市第一人民医院进行 3D-DSA检查的 86例动脉瘤病人作为研究对象，按照随机数字表法均分为低浓度组和常规浓度组。两组病人对比剂用量进行 3D-DSA检查。由两名医师对两组病人的连续减影图像、 MIP图像及 VR图像质量进行评价、对比，同时对两组病人在检查前、检查后 24 h和 48 h的血肌酐值( Scr)以及在检查后 24 h、48 h的 Scr升高值均行比较。结果低浓度组的动脉瘤显示率为 97.67%，常规浓度组的动脉瘤显示率为 100.00%。低浓度组在检查后 24 h的 Scr升高值( 4.63±0.78)μmol/L、48 h的 Scr升高值( 6.71±0.94)μmol/L均明显低于常规浓度组在检查后 24 h的 Scr升高值( 5.35±0.85) μmol/L、48 h的 Scr升高值( 8.14±1.19)μmol/L(P<0.05)。结论低浓度对比剂方案在 3D-DSA检查中能够显著降低碘摄入量以及对肾功能的影响，且不会因此降低图像质量。 |
| 英文摘要: |
| Objective To explore the application value of low-concentration contrast agent whole brain 3D digital subtraction angiography (3D-DSA) in the examination of patients with aneurysm.Methods Eighty-six patients with aneurysms undergoing 3D-DSA examination in Yibin First People's Hospital from February 2018 to April 2019 were assigned into low concentration group and routineconcentration group according to the random number table method. Two groups of patients were examined by 3D-DSA with different dosages of contrast agent. Two doctors evaluated and compared the quality of continuous subtraction image, MIP image and VR imageof the two groups, and compared the blood creatinine value (Scr) of the two groups before the examination and 24 h, 48 h after the examination, and compared the rising value of Scr at 24 h and 48 h after the examination.Results The display rate of aneurysm in low concentration group was 97.67%, and that in the routine concentration group was 100.00%. The increased Scr value at 24 h and 48 h afterthe examination in the low concentration group were (4.63±0.78) μmol/L and (6.71±0.94) μmol/L, which were significantly lower thanthose in the routine concentration group [(5.35±0.85) μmol/L and (8.14±1.19) μmol/L]. The difference was statistically significant (P< 0.05).Conclusion Low-concentration contrast agent used in the 3D-DSA examination of patients with suspected aneurysms can effectively reduce radiation concentration and the damage to renal function, and meanwhile does not reduce image quality. |
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