文章摘要
张 坤,吴永贵,郑 阔,等.249例急性肾损伤发病情况调查及相关因素分析[J].安徽医药,2015,19(10):1893-1896.
249例急性肾损伤发病情况调查及相关因素分析
Incidence survey and related factors of acute renal injury: An analysis of 249 cases
投稿时间:2015-04-25  
DOI:
中文关键词: 急性肾损伤  住院患者  发生率  危险因素
英文关键词: acute kidney injury  hospitalized patient  incidence  risk factor
基金项目:国家自然科学基金(No 81301660)
作者单位
张 坤 太和县中医院肾病科,安徽 阜阳 236600 
吴永贵 安徽医科大学第一附属医院肾脏科,安徽 合肥 230032 
郑 阔 太和县中医院肾病科,安徽 阜阳 236600 
周荣军 太和县中医院肾病科,安徽 阜阳 236600 
余冠华 太和县中医院肾病科,安徽 阜阳 236600 
龚睿琼 太和县中医院肾病科,安徽 阜阳 236600 
张 炜 安徽医科大学第一附属医院肾脏科,安徽 合肥 230032 
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中文摘要:
      目的 分析住院患者急性肾损伤(AKI)的流行特点及AKI发生的危险因素,为临床更好地认识和预防AKI、改善预后提供依据。方法 通过调查2013年1月1日—2013 年12月31日太和县中医院成年住院患者的肾功能检测结果,筛检出AKI患者,进行病史复习,回顾性分析住院患者AKI发生率、病因及分布特点;Logistic回归分析影响住院AKI患者病情严重程度的危险因素。结果 观察期间共有成年住院患者52 131例次,其中249例患者住院期间发生AKI,发病率为0.48%(249/52131)。患者男女患病比例1.96∶1。院内获得性AKI共58例,院外获得性AKI共191例。其中ICU 50例(占20.08%);妇产科3例(占1.20%);内科166例(占66.67%);外科30例(占12.05%)。AKI发病率随着年龄的增加逐渐增高,其中AKI患者病死率为11.24%。Logistic回归分析提示年龄、慢性肝病、慢性肾脏病是AKI预后可能的独立危险因素。 结论 住院患者AKI 的发病较常见,发病率随着年龄的增加逐渐增高,病死率较高。年龄、慢性肝病、慢性肾脏病是患者预后独立危险因素。
英文摘要:
      Objective To investigate the epidemiology and the risk factors of acute kidney injury (AKI) in hospitalized patients in order to help clinicians better understand and prevent AKI.Methods From the kidney function test results obtained from hospitalized patients of Taihe Hospital of Traditional Chinese Medicine from January 1,3 to December 31,3,we screened AKI patients to carry out the history review and retrospectively analyzed the incidence,etiology and distribution characteristics of these AKI patients; Logistic regression analysis was used to investigate the risk factors in severity of AKI.Results A total of 52131 person-time of hospitalized patients were observed,among which 249 patients (0.48%,249/52131) developed AKI.The male and female ratio was 1.96:1.191 cases were extramural hospital acquired AKI,and 58 cases were nosocomial acquired AKI,including 50 cases (20.08%) infected in ICU,3 cases (1.20%)in the department of obstetrics and gynecology,166 cases (66.67%) in the department of internal medicine and 30 cases (12.05%) in the surgical department.AKI incidence increased gradually with the increase of age,in which case fatality rate was 11.24%.Logistic regression analysis suggested age,chronic liver disease,chronic kidney disease (CKD) were independent risk factors for the prognosis of AKI.Conclusions The onset of hospitalized patients with AKI is common.The incidence rate increases gradually with the increase of age with a higher incidence of mortality.Age,chronic liver disease and chronic kidney disease (CKD) are independent risk factors for the prognosis of patients.
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