| 陈山.血必净注射液对重症肺炎病人的疗效及其对细胞免疫及炎性因子的影响[J].安徽医药,2017,21(1):127-129. |
| 血必净注射液对重症肺炎病人的疗效及其对细胞免疫及炎性因子的影响 |
| Effect of Xuebijing injection on cellular immunity and inflammatory factors in patients with severe pneumonia |
| 投稿时间：2016-05-21 |
| DOI： |
| 中文关键词: 血必净 重症肺炎 免疫 炎性因子 |
| 英文关键词: Xuebijing Severe pneumonia Immune Inflammation factor |
| 基金项目: |
|
| 摘要点击次数: 2217 |
| 全文下载次数: 660 |
| 中文摘要: |
| 目的 研究血必净注射液对重症肺炎病人的临床疗效,观察其对细胞免疫及炎性因子的影响,为临床治疗提供依据。方法 选取重症肺炎病人110例,按照随机数字表法将病人分为观察组和对照组,每组55例,对照组常规治疗,观察组加用血必净注射液治疗,比较两组临床疗效,比较治疗前后两组白细胞介素-1(IL-1)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、CD4+、CD8+以及自然杀伤细胞(NK)。结果 观察组总有效率96.4％显著高于对照组的80.0％(P＜0.05)；治疗后两组IL-1、IL-6和TNF-α显著低于治疗前(P＜0.05),且观察组显著低于对照组(P＜0.05)；治疗后两组CD4+、NK细胞显著升高,CD8+显著低于治疗前(P＜0.05),观察组CD4+、NK显著高于对照组(P＜0.05),CD8+显著低于对照组(P＜0.05)。结论 血必净注射液治疗重症肺炎具有较好的临床疗效,能降低炎性反应,增强细胞免疫。 |
| 英文摘要: |
| Objective To study the clinical curative effect of Xuebijing injection on patients with severe pneumonia,to observe the effect of Xuebijing on cellular immunity and inflammatory factors,and to provide basis for clinical treatment. Methods One hundred and ten cases of severe pneumonia were selected,the patients were divided into the study group and the control group,55 cases in each group.The control group received routine treatment,the study group were treated with Xuebijing injection combined with received routine treatment.The clinical effect of two groups were evaluated by comparing Interleukin 1 (IL-1) and interleukin 6 (IL-6),tumor necrosis factor-ɑ (TNF-ɑ),CD4+,CD8+ and natural killer (NK) cells before and after treatment in two groups. Results The total effective rate of the study group was 96.4％(53/55) ,which was significantly higher than that of 80.0％(44/55)in the control group (P<0.05).After treatment,IL-1,IL-6 and TNF-ɑ of two groups were significantly lower than those before treatment (P<0.05),and the study group was significantly lower than the control group (P<0.05).CD4+ and NK cells of two groups were significantly increased (P<0.05) after treatment,meanwhile CD8+ was significantly lower than before treatment (P<0.05),CD4+ and NK in the study group were significantly higher than those in the control group (P<0.05),CD8+ was significantly lower than the control group (P<0.05). Conclusion Xuebijing injection in the treatment of severe pneumonia has good clinical curative effect.It can reduce the inflammatory reaction,enhance the patient's cellular immunity. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
