文章摘要
李季,詹韵韵,郜玉峰,等.超声造影定位引导下肝癌射频消融治疗的临床价值[J].安徽医药,2017,21(2):290-293.
超声造影定位引导下肝癌射频消融治疗的临床价值
The clinical value of radiofrequency ablation of hepatocellular carcinoma guided by contrast-enhanced ultrasound
投稿时间:2016-10-07  
DOI:
中文关键词: 超声造影  射频消融  肝细胞癌  彩色超声
英文关键词: Contrast-enhanced ultrasound  Radiofrequency ablation  Hepatocellular carcinoma  Color ultrasound
基金项目:安徽省自然科学基金(1608085MH164)
作者单位E-mail
李季 安徽医科大学第二附属医院超声科,安徽 合肥 230601  
詹韵韵 安徽医科大学第二附属医院超声科,安徽 合肥 230601  
郜玉峰 安徽医科大学第二附属医院肝病科,安徽 合肥 230601  
彭梅 安徽医科大学第二附属医院超声科,安徽 合肥 230601  
姜凡 安徽医科大学第二附属医院超声科,安徽 合肥 230601 ahultrasound2005@126.com 
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中文摘要:
      目的 探讨肝脏超声造影术对肝癌实时引导下射频消融(RFA)治疗的临床应用价值。方法 选取行肝癌射频消融治疗的110例肝癌病人,对比观察应用常规彩超引导的51个病灶和超声造影技术(CEUS)实时引导下的59个病灶进行射频消融前后的临床疗效。结果 对110例肝癌病灶超声实时引导下的RFA均成功,无术后出血、肝脓肿、胆漏、针道转移、皮肤灼伤等并发症。以术后1个月行肝脏增强CT为检查标准,常规超声引导下的51个病灶一次性完全消融36个,完全消融率达70.6%,超声造影引导下的59个病灶完全消融54个,完全消融率达91.5%,两种引导方法的病灶完全消融率差异有统计学意义(χ2=8.06,P=0.005)。多因素非条件Logistic回归分析结果表明,超声造影引导方法是疗效的保护性因素,OR(95%CI):5.051(1.619~15.757),P=0.005。结论 超声造影引导下的RFA治疗效果优于常规超声引导的RFA。
英文摘要:
      Objective To evaluate the application value of contrast-enhanced ultrasound (CEUS) in the radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC). Methods 110 HCC patients treated by radiofrequency ablation were selected in the secord affiliated hospital of Anhui medical university.The RFA of hepatic carcinoma lesion was guided by conventional color ultrasound and CEUS.The rates of postoperative complete ablation were compared between the 51 lesions guided by conventional color ultrasound and the 59 lesions guided by CEUS. Results All the 110 case of contrast-enhanced ultrasound (CEUS) in RFA of HCC were success,which there are no complications such as postoperative bleeding,hepatapostema,bile leak,Needle metastasize.One month after operations,taken enhanced CT examination as standard,the complete ablation rate of RFA guided by conventional color ultrasound was 70.6%.The complete ablation rate of RFA guided by the CEUS was 91.5%.The comparison of complete ablation rates of lesions among 2 methods of imaging examination showed that the difference was statistically significant (χ2=8.06,P=0.005).Multi-factor unconditioned logistic regression analysis show that the RFA guided by CEUS is the only protective factors,OR (95%CI):5.051(1.619-15.757),P=0.006. Conclusion CEUS can significantly improve the operation effect in radiofrequency ablation for HCC.
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