| 袁洁,姚军,王磊,等.阿司匹林原料药一体化实验的探索与实践[J].安徽医药,2017,21(2):377-380. |
| 阿司匹林原料药一体化实验的探索与实践 |
| Exploration and practice on the integrative experiment of aspirin |
| 投稿时间：2016-06-15 |
| DOI： |
| 中文关键词: 药学实验 阿司匹林 一体化 教学改革 |
| 英文关键词: Pharmaceutical experiment Aspirin Integration Teaching reform |
| 基金项目:新疆医科大学Ⅶ教育教学改革与研究项目(YG2013053) |
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| 中文摘要: |
| 该文分析了药学专业实验教学的现状,并针对存在的问题对药物化学和药物分析学科开展一体化实验教学进行了初步的探索和实践。该实验基于“药品质量源于设计”的理念,以经典药物阿司匹林为焦点,设计并完成了阿司匹林原料药的合成及质量评价,同时和市售阿司匹林原料药的质量进行对比,进一步探讨了检测结果产生差异的原因。这一实验教学模式得到了学生的充分肯定,不仅激发了学生的实验兴趣,使学生深刻的认识到学科之间的内在联系,同时也提升学生对药品质量控制认识的高度,这对其今后从事药品的研发工作有着深远的意义。 |
| 英文摘要: |
| The status quo of pharmacy experimental teaching in Xinjiang Medical University was analyzed in this paper.The integrative experiment on pharmaceutical chemistry and pharmaceutical analysis was explored and practiced for the problems existing in experimental teaching.Based on the concept of “quality by design”,the experiment of synthesis and quality evaluation of aspirin was designed and practiced.The quality of marketed aspirin was also evaluated.At the same time,the causes of quality difference between aspirin synthesized by students and marketed aspirin were analyzed.By carrying out this integrative experiment,students′interest were stimulated in experiment,the intrinsic links between subjects was studied by students and students′understanding of drug quality control was promoted which had far-reaching significance for students to be engaged in drug research and development. |
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