| 朱敏,印五岳,李继武,等.术后持续镇静时间对自发性脑出血预后的影响[J].安徽医药,2017,21(3):490-492. |
| 术后持续镇静时间对自发性脑出血预后的影响 |
| Effect of sedation in different stages on the prognosis of intracerebral hemorrhage after operation |
| 投稿时间：2016-06-11 |
| DOI： |
| 中文关键词: 颅内出血 破裂,自发性 二异丙酚 预后 |
| 英文关键词: Intracranialhemorrhages Rupture,spontaneous Propofol Prognosis |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨自发性脑出血术后应用异丙酚镇静时间长短对其预后的影响。 方法 150例自发性脑出血手术病人分成镇静A组 (50例)、镇静B组 (50例)和未镇静组(50例),镇静A组病人术后予以异丙酚持续镇静6 h,镇静B组病人术后予以异丙酚持续镇静24 h,未镇静组未予以镇静,监测、记录三组病人术后6 h收缩压、舒张压、心率,肺部感染及再出血情况,记录病人术后6个月时日常生活活动能力(ADL)评分。 结果 术后6 h,镇静A组、镇静B组的收缩压,心率均低于未镇静组(均为P<0.05)；镇静B组术后6 h的舒张压低于未镇静组(P<0.05)。镇静A组的术后再出血率(8.0%)低于未镇静组(24.0%),差异有统计学意义(χ2=4.762,P=0.029),镇静B组的术后再出血率(6.0%)低于未镇静组(24.0%) (χ2=6.353,P=0.012)；镇静A组的肺部感染率(18.0%)低于镇静B组(36.0%) (χ2=4.110,P=0.043)；术后6个月时镇静A组的预后良好率(84.0%)高于镇静B组(66.0%)(χ2=4.320,P=0.038),更高于未镇静组(56.0%)(χ2=9.333,P=0.002)。镇静A组的预后不良率(16.0%)低于镇静B组(34.0%)(χ2=4.320,P=0.038),更低于未镇静组(44.0%)(χ2=9.333,P=0.002)。 结论 高血压脑出血术后予以异丙酚镇静6 h能够减少术后再出血的风险,减少肺部感染率,并改善预后。 |
| 英文摘要: |
| Objective To analyze the effect of propofol sedation in different stages on the prognosis of patients with intracerebral hemorrhage after operation. Methods A total of 150 postoperative patients with ICH were assigned into sedation group A (50 cases),sedation group B (50 cases) and no-sedation group (50 cases).The patients of sedation group Awere given propofol to sedate in 6 hours,sedation group Bgiven propofol to sedate in 24 hours after surgery,and no-sedation group not given propofol to sedate.The systolic blood pressure,diastolic blood pressure and heart rate within 6hours after surgery were measured,and postoperative complications such as pulmonary infection and recurrent hemorrhage were also recorded.The ADL scores were followed at 6 months after surgery. Results Systolic blood pressure and heart rate at 6 hours after surgery of sedation group Aand sedation group Bwere lower than no-sedation group (all P<0.05);Diastolic blood pressure of sedation group B 6 hours after surgery was lower than no-sedation group (P<0.05).The rate of postoperative recurrent hemorrhage of sedation group A(8.0%) was lower than that of no-sedation group(24.0%) (χ2=4.762,P=0.029).The rate of postoperative recurrent hemorrhage of sedation group B(6.0%)was lower than that of no-sedation group(24.0%)(χ2=6.353,P=0.012).The rate of pulmonary infection of sedation group A(18.0%)was lower than that of sedation group B(36.0%) (χ2=4.110,P=0.043).The rate of favourable prognosis of sedation group A(84.0%) was higher than that of sedation group B(66.0%)(χ2=4.320,P=0.038),and even much higher than that of no-sedation group(56.0%)six months after surgery (χ2=9.333,P=0.002).The rate of unfavourable prognosis of sedation group A(16.0%) was lower than that of sedation group B(34.0%) (χ2=4.320,P=0.038),and even much lower than that of no-sedation group(44.0%)six months after surgery (χ2=9.333,P=0.002). Conclusions The sedation of propofol in intracerebral hemorrhage for 6 hours can reduce the risk of recurrent hemorrhage,reduce the rate of lung infection and improve the prognosis. |
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