| 江勇.荧光法在乳腺癌前哨淋巴结活检中的应用[J].安徽医药,2017,21(4):676-678. |
| 荧光法在乳腺癌前哨淋巴结活检中的应用 |
| Application value of fluorescence method in SLNB of breast cancer |
| 投稿时间：2016-05-30 |
| DOI： |
| 中文关键词: 荧光法 乳腺癌 前哨淋巴结 活检 |
| 英文关键词: Fluorescence spectrometry Breast cancer Sentinel lymph node Biopsy |
| 基金项目: |
|
| 摘要点击次数: 1761 |
| 全文下载次数: 548 |
| 中文摘要: |
| 目的 探讨荧光法在乳腺癌前哨淋巴结活检(SLNB)中的应用价值。方法 选择经病理学确诊的乳腺癌病人70例作为研究对象,采用随机数字表法分为荧光法组(病人采用荧光法寻找前哨淋巴结)、美蓝组(采用美蓝染色寻找前哨淋巴结),各35例,若病人前哨淋巴结病检阳性则进行腋窝淋巴结清扫术,对比两种方法检出前哨淋巴结的准确性。结果 荧光法组共发现成功检出31例前哨淋巴结病人,检出率88.57%,其中4例病人未发现发光淋巴结,美蓝组共成功检出23例前哨淋巴结病人,检出率65.71%,荧光法组前哨淋巴结检出率高于美蓝组,差异有统计学意义(P<0.05)；荧光法组与美蓝组检出时间比较,差异无统计学意义(P>0.05)；荧光法组共检出前哨淋巴结82枚,其中16例病人43枚淋巴结阳性,阳性率52.43%,美蓝组共检出前哨淋巴结65枚,其中11例病人23枚淋巴结阳性,阳性率35.38%,荧光法组的前哨淋巴结肿瘤转移阳性率高于美蓝组,差异有统计学意义(P<0.05)；荧光法组漏诊率5.55%低于美蓝组的38.89%,差异有统计学意义(χ2=5.786,P=0.016<0.05)。结论 荧光法在乳腺癌SLNB检查中检出率明显高于美蓝染色,具有较高的临床价值。 |
| 英文摘要: |
| Objective To explore the application value of fluorescence method in sentinel lymph node biopsy (SLNB) in breast cancer.Methods Seventy patients of breast cancer were confirmed by pathology were randomly assigned into fluorescence group (patients with fluorescence method for finding the sentinel lymph node),methylene blue Group (patients with methylene blue staining for finding the sentinel lymph node),35 patients in each group.If the patient was positive in sentinel lymph node disease detection axillary lymph node dissection was conducted.The detection accuracy of sentinel lymph node was comparedbetween the two methods.Results In fluorescence group 31 patients were successfully detected with sentinel lymph node,the detection rate being 88.57%,of which 4 patients hadno glowing lymph node.In methylene bluegroup 23 patients were successfully detected with sentinel lymph node,the detection rate being 65.71 percent.The detection rate of fluorescence group was significantly higher than that of methylene bluegroup (P<0.05).There was no statistically significant difference in detection time between two groups(P>0.05).In fluorescence group 82 sentinel lymph nodes were found,including 16 patients with lymph node-positive,the positive rate being 52.43%.In methylene bluegroup 65 sentinel lymph nodes were found,in which 11 patients were positive,the postive rate being 35.38%.Sentinel lymph node metastasis positive rate influorescence group was significantly higher than that in methylene blue group;the difference was statistically significant (P<0.05).The rate of misdiagnosis in fluorescence group was significantly lower than the methylene blue group (5.55% vs 38.89%);the difference was statistically significant (χ2=5.786,P=0.016<0.05).Conclusions Thedetection rate of fluorescence detecting SLNB in breast cancer is significantly higher than the detection rate of methylene blue staining,which has high clinical value. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
