| 胡凌锋,刘丽.N端脑利钠肽前体在肺部感染患者机械通气中的指导作用[J].安徽医药,2017,21(9):1619-1622. |
| N端脑利钠肽前体在肺部感染患者机械通气中的指导作用 |
| The guiding role of NT-PROBNP in the mechanical ventilation of patients with lung infection |
| 投稿时间：2017-06-09 |
| DOI： |
| 中文关键词: N端脑利钠肽前体 肺部感染 机械通气 心衰分级 |
| 英文关键词: NT-PROBNP Lung infection Mechanical ventilation The classification of heart failure |
| 基金项目: |
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| 中文摘要: |
| 目的 研究N端脑利钠肽前体(NT-PROBNP)对患者采用机械通气及脱机治疗时机的指导意义。方法 选取使用呼吸机的肺部感染患者48例,测定患者使用呼吸机前、使用呼吸机时、成功撤机后的动脉血NT-PROBNP浓度及相对应的患者心衰分级,观察并比较患者血液中NT-PROBNP浓度的变化及心衰程度的改变。结果 患者使用呼吸机前的NT-PROBNP浓度及心衰分级小于使用呼吸机时的NT-PROBNP浓度及心衰分级(P<0.001)；成功撤机后的NT-PROBNP浓度及心衰分级小于使用呼吸机时的NT-PROBNP浓度及心衰分级(P<0.001)。结论 NT-PROBNP对肺部感染患者是否采用机械通气及脱机治疗具有指导意义。 |
| 英文摘要: |
| Objective To explore the guiding role of NT-PROBNP in the mechanical ventilation of patients with lung infection. Methods We chose 48 patients with lung infection who were treated with ventilator,measured the arterial blood concentration of NT-PROBNP and the classification of patients′ heart failure before,during and after the use of ventilator,observed and compared the change of the arterial blood concentration of NT-PROBNP and the degree of heart failure. Results Blood concentration of NT-PROBNP and the heart failure classification were lower before the use of ventilator than during the use of ventilator(P<0.001). Blood concentration of NT-PROBNP and the heart failure classification were lower after the use of ventilator than during the use of ventilator(P<0.001). Conclusions The NT-PROBNP can provide a reference to mechanical ventilation of patients with lung infection. |
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