磁共振灌注加权成像在原发性痛经子宫肌层血流动力学研究中的应用

陈艳; 崔利; 何江波; 吴晓燕; 彭雨彬; 王岩; 王磊君

文章摘要

陈艳,崔利,何江波,等.磁共振灌注加权成像在原发性痛经子宫肌层血流动力学研究中的应用[J].安徽医药,2017,21(12):2200-2203.

磁共振灌注加权成像在原发性痛经子宫肌层血流动力学研究中的应用

Application of MR perfusion weighted imaging in the study of myometrium artery hemodynamics of primary dysmenorrheaCHEN Yan¹,CUI Li¹,HE Jiangbo¹,WU Xiaoyan²,PENG Yubin¹,WANG Yan¹,WANG Leijun¹ (1.Department of Radiology,Baoshan District Chinese Traditional and Western Medicine Hospital, Shanghai 201900,China;2.Department of Radiology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China) Abstract:Objective

投稿时间：2016-08-25

DOI：

中文关键词: 磁共振灌注原发性痛经血流动力学应用

英文关键词: Magnetic resonance perfusion Primary dysmenorrhea Hemodynamics Application

基金项目:

作者	单位
陈艳	上海市宝山区中西医结合医院放射科,上海 201900
崔利	上海市宝山区中西医结合医院放射科,上海 201900
何江波	上海市宝山区中西医结合医院放射科,上海 201900
吴晓燕	上海中医药大学附属曙光医院放射科,上海 201203
彭雨彬	上海市宝山区中西医结合医院放射科,上海 201900
王岩	上海市宝山区中西医结合医院放射科,上海 201900
王磊君	上海市宝山区中西医结合医院放射科,上海 201900

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中文摘要:

目的运用磁共振灌注加权成像技术探讨原发性痛经患者痛经发作期子宫肌层血流动力学特点。方法对符合选择标准的原发性痛经患者30例及正常志愿者19例进行子宫常规磁共振成像扫描及子宫肌层磁共振灌注加权成像检查,分别获取子宫内部肌层及外部肌层感兴趣区的时间-信号强度(TIC)曲线及灌注参数。采用SPSS13.0软件进行两独立样本Wilcoxon秩和检验,P＜0.05表示差异有统计学意义。结果痛经组在发作期内部肌层与外部肌层的TIC曲线大致相似,在注入造影剂后即出现一段陡峭的上升段,然后为一段时间较长的缓慢上升段,达到峰值后进入较为平缓的平台期。对照组在注入造影剂后即出现一段较为陡峭的上升段,然后内部肌层快速达到峰值随即开始下降；而外部肌层继续经历一段相对缓慢的上升段达到峰值后进入较为平缓的平台期。痛经组与对照组的子宫内部肌层的峰值时间差异有统计学意义(P=0.031),子宫外部肌层的峰值时间及子宫内、外部肌层强化峰值差异无统计学意义(P=0.050 3、0.075 0、0.067 1)。结论痛经发作期子宫内部肌层的动脉,尤其是细小动脉的血流阻力显著增加,这可能是引发痛经的重要因素。

英文摘要:

Objective To explore the characteristics of myometrium artery hemodynamics of primary dysmenorrhea (PD) patients. Methods MRI routine scanning and perfusion imaging were performed in 30 patients with PD and 19 normal volunteers.Perfusion parameter and TIC curve of MR perfusion in ROI of inner myometrium and outer myometrium were obtained.The Wilcoxon test was performed with SPSS version 13.0,statistical significance was set at P＜0.05. Results In 30 patients with PD,the TIC curves of inner myometrium and outer myometrium were similar,which showed obvious steep up slope at the first phase,then a long gentle steep up slope,and finally a plateau after peak value.In 19 normal volunteers,the results showed that obvious steep up slopes were seen both in inner myometrium and outer myometrium at the first phase,and then inner myometrium began to decline after quick peak,while the outer myometrium went through a long gentle steep up slope,and reached a plateau after peak value.The median of the TTP value of inner myometrium had significant difference between PD group and normal group.The median of the TTP value of outer myometrium and the median of the PH value of both inner and outer myometrium had no differences between PD group and normal group (P=0.050 3,0.075 0,0.067 1,respectively). Conclusions The blood flow resistance of artery,especially small artery of inner myometrium was significantly increasing when dysmenorrhea attack,which may be the main factor of primary dysmenorrhea.

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