| 刘宗涛,刘涛,谢丹,等.H型高血压患者血压晨峰现象与早期肾功能损害的关系[J].安徽医药,2017,21(12):2238-2241. |
| H型高血压患者血压晨峰现象与早期肾功能损害的关系 |
| Relationship between morning blood pressure surge phenomenon in patients with type Hhypertension and the early renal damage |
| 投稿时间：2017-03-14 |
| DOI： |
| 中文关键词: H型高血压 血压晨峰 早期肾损害 |
| 英文关键词: H-type hypertension Morning blood pressure surge Early renal damage |
| 基金项目:武汉市卫生计生委科研资助项目(WX15D20)H型高血压患者血压晨峰现象与早期肾功能损害的关系刘宗涛,刘涛,谢丹,汪志新,崔跃,魏莱,余敏,黎鹏飞 (武汉市红十字会医院心血管内科,湖北 武汉 430015)H型高血压患者血压晨峰现象与早期肾功能损害的关系L 刘宗涛,刘涛,谢丹,汪志新,崔跃,魏莱,余敏,黎鹏飞 |
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| 中文摘要: |
| 目的 探讨具有晨峰现象的H型高血压与早期肾功损害关系。方法 选择已确诊H型高血压[同型半胱氨酸(Hcy)≥10 μmol·L-1]者共210例,对这些患者行24 h动态血压监测(ABPM),根据监测结果将患者分为晨峰组(108例)和非晨峰组(102例),检测各组受试者血清胱抑素C水平以及尿β2-微球蛋白的含量,同时检测一般生化指标。结果 晨峰组24 h平均收缩压[(155.7±14.6) mmHg]、白昼平均收缩压[(160.4±15.5) mmHg]、夜间平均收缩压[(147.7±16.5) mmHg]、收缩压晨峰[(35.4±7.2) mmHg]、尿β2-微球蛋白[(1.11±0.31) mg·L-1]及血清半胱氨酸蛋白酶抑制剂C[(1.86±1.04) mg·L-1]均高于非晨峰组(P＜0.05)。结论 H型高血压患者中具有血压晨峰者较非血压晨峰者更易出现早期肾功能损害。 |
| 英文摘要: |
| Objective To investigate the relationship between morning blood pressure surge (MBPS) phenomenon in patients with type Hhypertension and the early renal damage.Methods Two hundred and ten cases of type Hwere selected (Hcy≥10 μmol·L-1) for 24-hour ambulatory blood pressure monitoring (ABPM),who were assigned into the MBPS group with 108 patients and non-MBPS group with 102 patients according to the monitoring results. The serum cystatin Cand urinary beta 2- microglobulin and the general biochemical indexes were detected.Results The 24-hour mean systolic blood pressure [(155.7±14.6) mmHg],daytime average systolic blood pressure [(160.4±15.5) mmHg],nighttime average systolic blood pressure [(147.7±16.5) mmHg],morning peak systolic blood pressure [(35.4±7.2) mmHg],urine beta 2- microglobulin ([1.11±0.31) mg·L-1] and Cys-C [blood (1.86±1.04) mg·L-1] in MBPS group were higher than those of non-MBPS group (P＜0.05).Conclusions Of patients with type Hhypertension the ones who have morning blood pressure surge were more likely to have early renal damage than those who did not have morning blood pressure surge. |
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