| 朱婉秋.交叉性小脑神经机能联系不能的动脉自旋标记灌注成像分析[J].安徽医药,2017,21(12):2246-2249. |
| 交叉性小脑神经机能联系不能的动脉自旋标记灌注成像分析 |
| Arterial spin labeling perfusion imaging in crossed cerebellar diaschisisZHU Wanqiu (Department of Radiology,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230022,China) Abstract:Objective |
| 投稿时间：2016-09-21 |
| DOI： |
| 中文关键词: 脑梗死 动脉自旋标记 交叉性小脑神经机能联系不能 |
| 英文关键词: Cerebral infarction Arterial spin labeling Crossed cerebellar diaschisis |
| 基金项目: |
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| 中文摘要: |
| 目的 通过3.0T磁共振三维动脉自旋标记成像(ASL)评估不同期幕上脑梗死体积(CIV)、梗死区灌注异常程度与交叉性小脑神经机能联系不能(CCD)的关系。 方法 收集单侧幕上脑梗死患者52例,其中急性期13例、亚急性期26例、慢性期13例。所有患者进行磁共振常规扫描、弥散加权成像(DWI)、磁共振血管成像(MRA)及ASL检查,记录并计算幕上CIV、幕上梗死区脑灌注与镜像区正常脑组织灌注差值和幕下小脑不对称指数(AI)。以AI＞10%诊断CCD阳性,分析CCD阳性组与阴性组患者不同期幕上CIV及梗死区灌注异常程度的差异,分析CCD阳性组患者不同期幕上CIV、梗死区灌注异常程度与幕下小脑AI的相关性。 结果 急性期、亚急性期和慢性期脑梗死患者CCD发生率分别为46.2%、42.3%、61.5%。不同期CCD阳性组患者幕上CIV均高于阴性组患者,但差异无统计学意义(P＞0.05)。急性期CCD阳性组患者幕上梗死区灌注降低程度与CCD阴性组患者差异有统计学意义(P=0.015),亚急性期和慢性期患者幕上梗死区灌注降低程度与阴性组患者差异无统计学意义(P＞0.05)。CCD阳性组患者各期幕上CIV、梗死程度与幕下小脑AI无明显相关性。 结论 急性期幕上脑梗死区灌注降低程度与CCD发生有关,但是与CCD的严重程度不具有相关性。不同期幕上CIV与CCD的发生无明显关系。 |
| 英文摘要: |
| Objective To assess the relationship between the supratentorial cerebellar infarction volume (CIV) and extent of infarction with abnormal perfusion and crossed cerebellar diaschisis (CCD) in different stages of cerebral infarction by 3.0T 3-dimensional MR arterial spin labeling (ASL). Methods Fifty-two patients with unilateral supratentorial cerebral infarction were selected,including 13 cases of acute cerebral infarction,26 cases of subacute infarction and 13 cases of chronic infarction who all had undergone conventional MR scans,diffusion weighted imaging (DWI),magnetic resonance angiography (MRA) and arterial spin-labeling.Supratentorial CIV,the difference between supratentorial cerebral perfusion in the infarction area and normal brain perfusion and subtentorial cerebellar asymmetry index (AI) were measured and recorded.CCD positive group was diagnosed with AI more than 10%.Supratentorial CIV and the change degree of hypoperfusion of CCD positive and CCD negative groups in different stages of cerebral infarction were compared.Besides,we analyzed the dependability between supratentorial CIV and the change degree of hypoperfusion with cerebellum AI in different stages of cerebral infarction in CCD positive group. Results The incidence rates of CCD in acute,subacute and chronic stage were 46.2%,42.3% and 61.5%,respectively.In different stages of infarction,median supratentorial CIV of CCD positive group was higher than that of CCD negative group,but there were no significant differences (P＞0.05).Significant difference was found in the change degree of supratentorial hypoperfusion between CCD positive and CCD negative group (P=0.015) in acute stage,and no significant difference (P>0.05) was observed in subacute and chronic stage.There was no correlation between supratentorial CIV or the change degree of hypoperfusion and subtentorial cerebellar AI. Conclusions The extent and severity of supratentorial lesion in patients with acute cerebral infarction may lead to the occurrence of CCD rather than the magnitude of CCD.The supratentorial CIV may not result in the occurrence of CCD in patients with different stages of cerebral infarction. |
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