| 张慎和.双能量CT对原发性肝癌化疗栓塞术治疗后疗效评价的研究[J].安徽医药,2018,22(9):1787-1789. |
| 双能量CT对原发性肝癌化疗栓塞术治疗后疗效评价的研究 |
| Study of dual energy CT on efficacy of TACE in patients with HCC |
| 投稿时间：2017-03-28 |
| DOI： |
| 中文关键词: 双能量CT 原发性肝癌 化疗栓塞术 |
| 英文关键词: Dual energy CT Hepatocellular carcinoma Transcatheter arterial chemoembolization |
| 基金项目:河北省医学科学重点项目(20150753)双能量CT对原发性肝癌化疗栓塞术治疗后疗效评价的研究张慎和 (衡水市中医医院,河北 衡水 053000) |
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| 中文摘要: |
| 目的 探究双能量CT(DECT)评价原发性肝癌肝动脉化疗栓塞治疗疗效的价值。方法 对原发性肝癌30例进行化疗栓塞,于术后4周行DECT及数字减影血管造影(DSA)检查,了解患者肝脏病灶情况。对DECT图像分别采用双能量成像处理法(A法)和常规成像处理(B法),根据病灶碘油缺损区和(或)周边区强化显示结果进行评分,并DECT检查结果与 DSA检查结果进行对比分析。结果 A法取得图片的评分显著高于B法(P<0.05)。DSA检出42个病灶,A法和B法分别检测出38个和32个病灶； A法的病灶阳性检出率为90.5%、敏感性为90.5%、特异性为86.0%,显著高于B法(阳性病灶检出率为76.2%、敏感性为76.2%、特异性为58.0%)(P<0.05)。结论 DECT对原发性肝癌肝动脉化疗栓塞术的治疗效果展现出较高的准确性,该研究为原发性肝癌化疗栓塞术疗效评价方案的制定提供了思路。 |
| 英文摘要: |
| Objective To study the dual energy CT (DECT) on efficacy of transcatheter arterial chemoembolization (TACE) in patients with(hepatocellular carcinoma,HCC).Methods 30 patients of HCC undergoing TACE were chosen.DECT and DSA were used to detect the number of niduses in liver on 4 weeks post-TACE.The images were processed by the methods of dual energy imaging (method A) and routine imaging (method B).The images of the two methods were graded according to nidus and its ambitus (more scores mean more distinct).The results of the two methods and DSA were compared and statistical analysis.Results The score of method Awas higher than method Bsignificantly (P<0.05).DAS detected 42 niduses,and method A,method Bdetected 38 niduses and 32 niduses,respectively.Statistical analysis showed that the nidus positive rate,sensibility and specificity of method Awere 90.5%,90.5% and 86.0%,respectively,which were significantly higher than those of method B (nidus positive rate,sensibility and specificity were 76.2%,76.2% and 58.0%,respectively) (P<0.05).Conclusion DECT exhibits favorable veracity on assessing the efficacy of TACE in patients with HCC,and this study provides idea for the assessment of efficacy about the TACE. |
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