| 张晓文,朱磊.无创正压通气治疗重症手足口病40例疗效观察[J].安徽医药,2019,23(5):873-875. |
| 无创正压通气治疗重症手足口病40例疗效观察 |
| Observation on 40 cases with severe hand foot and mouth disease treated by noninvasive positive pressure ventilation |
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| DOI：10.3969/j.issn.1009-6469.2019.05.008 |
| 中文关键词: 手足口病 连续气道正压通气 氧吸入疗法 面罩 利钠肽,脑 |
| 英文关键词: Severe hand foot and mouth disease Continuous positive airway pressure Oxygen inhalation therapy Masks Natriuretic peptide,brain |
| 基金项目:江苏省卫生计生委医学科研课题(Q201617) |
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| 中文摘要: |
| 目的 探讨无创正压通气治疗重症手足口病的效果。方法 将2014年4月至2015年10月徐州市儿童医院收治的68例重症手足口病病儿作为研究对象,其中观察组40例应用无创正压通气治疗,对照组28例使用面罩或鼻导管给氧治疗,观察比较两组病儿临床疗效、血清脑钠肽水平、退热时间、心率及血压恢复正常所用时间。结果 观察组总有效率为82.5%,高于对照组的60.7%,差异有统计学意义(P＜0.05);观察组退热时间为(3.30±1.07)d,心率恢复正常所用时间为(3.50±1.09)d,血压恢复正常所用时间为(3.37±1.17)d,均短于对照组(P＜0.01);治疗24 h后观察组脑钠肽水平较对照组显著下降(P＜0.01)。结论 重症手足口病病儿在综合治疗的基础上早期进行无创正压通气治疗,可加快生命体征的各项指标恢复正常,提高治疗有效率。 |
| 英文摘要: |
| Objective To explore the effect of noninvasive positive pressure ventilation in the treatment of severe hand foot and mouth disease (HFMD) and nursing measures.Methods 68 children with severe HFMD in Xuzhou Children--s Hospital from April 2014 to October 2015 were studied,40 cases treated by noninvasive positive pressure ventilation as observation group,28 cases with oxygen inhalation through nasal catheter or mask as control group.The effective rate,serum brain natriuretic peptide (BNP) level,the defervescence time,the time of heart rate and blood pressure returned to normal in the two groups were compared.Results The total effective rate of the observation group was 82.5%,and was higher than that in the control group (P＜0.05).The-defervescence time of the observation group was (3.30±1.07) d,the time of heart rate returned to normal was (3.50±1.09) d,the time of blood pressure returned to normal was (3.37±1.17)d,which were shorter than those in the control group(P＜0.01).The level of BNP in the observation group was significantly lower than that in the control group after 24h treatment (P＜0.01).Conclusion Early noninvasive positive pressure ventilation combined with conventional treatment for severe HFMD,while the full implementation of nursing measures,can accelerate the recovery of vital signs and improve the effective rate of treatment. |
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