| 张娇,谭友慧,高静,等.子宫动脉及内膜血流参数与人工周期冻融胚胎移植结局的关系[J].安徽医药,2020,24(2):323-326. |
| 子宫动脉及内膜血流参数与人工周期冻融胚胎移植结局的关系 |
| Relationship between uterine artery and endometrial blood flow and the outcome of FET with artificial cycle |
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| DOI：10.3969/j.issn.1009?6469.2020.02.028 |
| 中文关键词: 胚胎移植 妊娠结局 人体质量指数 血管阻力 血液流变学 超声检查，多普勒，彩色 子宫内膜 子宫动脉 |
| 英文关键词: Embryo transfer Pregnancy outcome Body mass index Vascular resistance Hemorheology Ultrasonogra? phy,doppler,color Endometrium Uterine artery |
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| 中文摘要: |
| 目的探讨子宫动脉及内膜血流参数与人工周期冻融胚胎移植( FET)结局的关系。方法选取 2017年 5月至 2018年 4月青岛市市立医院行人工周期 FET治疗的病人 82例，于内膜转化日检测子宫动脉及内膜血流参数，根据 FET结局及体质量指数( BMI)不同进行分组，比较组间子宫动脉及内膜血流参数的差异。结果未妊娠组与临床妊娠组间比较，子宫动脉阻力指数( RI)、搏动指数( PI)及内膜血流指数( FI)、血管血流指数( VFI)差异有统计学意义( P＜0.05)子宫内膜容积( V)、子宫动脉收缩期峰值流速( PSV)、舒张末期流速( EDV)、计算收缩期峰值 /舒张末期流速( S/D)及内膜血管指数，(VI)差异无统计学意义( P＞ 0.05)，子宫动脉 RI及内膜 FI、VFI对 FET结局具有预测效能( P＜0.05)，子宫动脉 PI对 FET结局不具有预测效能( P＞0.05)， BMI＜25 kg/m2组与 BMI≥25 kg/m2组比较，临床妊娠率、子宫动脉 RI、PI及内膜 FI、VFI差异有统计学意义( P＜0.05)。结论人工周期 FET转化日子宫动脉 RI、PI值较低和内膜 FI、VFI较高是临床妊娠的有利条件，子宫动脉 RI及内膜 FI、VFI对 FET结局具有预测效能，肥胖病人临床妊娠率下降可能与子宫动脉及内膜血流参数异常有关。 |
| 英文摘要: |
| Objective To explore the relationship between uterine artery and endometrial blood flow and the outcome of frozen? thawed embryo transfer(FET)with artificial cycle.Methods Eighty?two patients with FET with artificial cycle in Qingdao Munici?pal Hospital from May 2017 to April 2018 were collected.Uterine artery and endometrial blood flow parameters were measured onendometrial transformation day.Patients were assigned into the two groups according to the outcome of FET and body mass index(BMI).The difference of parameters of uterine artery and endometrial blood flow were detected and compared between different groups.Results There were statistical difference in the resistance index(RI)，pulse index(PI)of the uterine artery and the blood flow index(FI)，blood vessels flow index(VFI)of the endometrium between the non?pregnancy and the clinical pregnancy group(P＜0.05)but the endometrial volume(V)peak systolic velocity(PSV)end?diastolic velocity(EDV)，peak systolic/end?diastol? icvelocity(S，/D)oftheuterinearteryandthe，vascularindex(VI)ofendom，etrium were not statistically different(P＞0.05).The RI of uterine artery and FI，VFI of endometrium were forecasting efficacy to the outcome of FET(P＜0.05)，but the PI of uterine artery was not forecasting efficacy(P＞0.05). The clinical pregnancy rate and the indicators including RI，PI of uterine artery and FI，VFI of endometrium were statistically different between the BMI＜25 kg/m2 and BMI≥25 kg/m2 group(P＜0.05).Conclusion The lower level of the RI，PI of uterine artery and the higher level of the FI，VFI of endometrium are more likely to get pregnancywhen the endometrium were transformed by progesterone in FET with artificial cycle.The RI of uterine artery and the FI，VFI of en? dometrium are indicators to predict the outcome of FET.The decreased pregnancy rate in obese patients may be related to abnormalblood flow parameters of uterine arteries and endometrium. |
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