| 俞楚仪,刘佳,黄诗雅,等.运动对多囊卵巢综合征代谢和生殖内分泌影响的 Meta分析[J].安徽医药,2020,24(4):637-641. |
| 运动对多囊卵巢综合征代谢和生殖内分泌影响的 Meta分析 |
| A meta analysis of exercise on metabolism and reproductive endocrine in polycystic ovary syndrome |
| |
| DOI：10.3969/j.issn.1009?6469.2020.04.001 |
| 中文关键词: 多囊卵巢综合征 运动 代谢 生育力 胰岛素抗药性 性激素结合球蛋白 人体质量指数 腰臀比 Meta分析 |
| 英文关键词: Polycystic ovary syndrome(PCOS) Exercise Metabolism Fertility Insulin resistance Sex hormone? binding globulin Body mass index Waist?hip ratio Meta?analysis |
| 基金项目:广东省省级科技计划项目(2017A020213004) |
|
| 摘要点击次数: 2094 |
| 全文下载次数: 601 |
| 中文摘要: |
| 目的系统评价运动对多囊卵巢综合征( PCOS)病人代谢和生殖内分泌的影响。方法计算机检索 PubMed、Cochrane Library、EMbase、中国生物医学文献数据库、中国知网数据库、维普数据库，纳入关于运动干预 PCOS的临床随机对照研究，检索时间截至 2019年 1月。在筛选文献、数据提取和质量评价后，使用 RevMan 5.3软件进行 Meta分析。结果共纳入 8项临床随机对照研究，总计 373例 PCOS病人。 Meta分析结果显示:与 PCOS空白对照组相比， PCOS运动干预组前后变化值显示运动可以降低体质量指数( BMI)(MD＝-0.38，95%CI＝-0.73～-0.03，P＝0.03)、腰臀比( WHR)(MD＝-0.03，95%CI＝-0.06～0.00，P＝0.02)、空腹胰岛素(FI)(MD＝-2.19，95%CI＝--3.06～-1.31，P＜0.000 01)、胰岛素抵抗指数( HOMA?IR)(MD＝-1.02，95%CI＝ -1.5～-0.54，P＜0.000 1)、低密度脂蛋白( LDL?C)(MD＝-0.15，95%CI＝-0.29～-0.01，P＝0.03)水平，提高高密度脂蛋白(HDL?C)(MD＝0.12，95%CI＝0.03～0.22，P＝0.01)和性激素结合球蛋白( SHBG)(MD＝2.11，95%CI＝0.63～3.59，P＝0.005)水平。结论运动干预可以改善 PCOS病人代谢和生殖内分泌指标，且对代谢指标的改善范围更广泛。 |
| 英文摘要: |
| Objective To systematically evaluate the effects of exercise on metabolism and endocrine in patients with polycystic ova? ry syndrome(PCOS).Methods Literature in PubMed，Cochrane Library，EMbase，Chinese Biomedical Literature Database，China Knowledge Network Database，and Weipu Database till January 2019 were retrieved.Clinical randomized controlled trials on exer?cise intervention of PCOS were included.Meta?analysis was performed using RevMan 5.3 software after literature screening，data ex? traction，and quality evaluation.Results A total of 8 clinical randomized control studies were included，with a total of 373 PCOS patients.According to meta?analysis results，compared with the PCOS blank control group，the changes in the PCOS exercise inter? vention group showed that exercise could reduce the body mass index(BMI)( MD＝-0.38，95% CI＝-0.73～-0.03，P＝0.03)， waist?to?hip ratio(WHR)( MD＝-0.03，95% CI＝-0.06～0.00，P＝0.02)，fasting insulin(FI)( MD＝-2.19，95% CI＝--3.06～ -1.31，P＜0.000 01)，insulin resistance index(HOMA?IR)( MD＝-1.02，95% CI＝-1.5～-0.54，P＜0.000 1)，level of low?density lipoprotein(LDL?C)( MD＝-0.15，95%)CI＝-0.29～-0.01，P＝0.03)，and increase the levels of high?density lipoprotein(HDL?C)(MD＝0.12，95% CI＝0.03～0.22，P＝0.01)and sex hormone binding globulin(SHBG)( MD＝2.11，95% CI＝0.63～3.59，P＝0.005).Conclusion Studies have shown that exercise intervention can improve some metabolic and reproductive endocrine indica?tors in patients with PCOS，and the improvement of metabolic indicators is more extensive. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
