| 陈进.中药熏蒸联合玻璃酸钠注射对膝骨关节炎病人膝关节功能及预后的影响[J].安徽医药,2020,24(6):1232-1235. |
| 中药熏蒸联合玻璃酸钠注射对膝骨关节炎病人膝关节功能及预后的影响 |
| Effect of herbal fumigation combined with sodium hyaluronate injection on knee function and prognosis in knee osteoarthritis patients |
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| DOI：10.3969/j.issn.1009?6469.2020.06.043 |
| 中文关键词: 骨关节炎，膝 中药熏蒸 玻璃酸钠 复发 预后 |
| 英文关键词: Osteoarthritis,knee Herbal fumigation Sodium hyaluronate Recurrence Prognosis |
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| 中文摘要: |
| 目的观察中药熏蒸联合玻璃酸钠注射对膝骨关节炎病人膝关节功能及预后的影响。方法选取 2017年 2月至 2018年 2月太和县人民医院膝骨关节炎病人 138例，按治疗方式分为两组，对照组 75例采用玻璃酸钠膝关节腔注射治疗，中药熏蒸组 63例采用中药熏蒸联合玻璃酸钠膝关节腔注射治疗。治疗 5周后观察两组临床疗效、膝关节功能、疼痛及不良反应的差异，选择两组治疗 5周后治愈和显效的病人进行 1年的疾病复发随访。结果治疗后 5周，与对照组相比，中药熏蒸组总有效率提高［ 98.4%比 88.0%，P＜0.05］Lysholm膝关节评分提高［(86.9±5.1)分比( 75.6±6.2)分， P＜0.05］目测类比评分降低［(3.2±0.5)分比( 4.6±0.9)分， P＜0.05］不良，反应发生率降低( 6.3%比 18.7%，P＜0.05)。随访结果显示，中药，熏蒸组治疗后 1年内疾病总复发率和累积复发率显著低于，对照组( P＜0.05)。结论中药熏蒸联合玻璃酸钠注射可有效改善膝骨关节炎病人的膝关节功能，降低治疗后 1年内的复发率，预后作用较好。 |
| 英文摘要: |
| Objective To observe the effect of herbal fumigation combined with sodium hyaluronate injection on knee function andprognosis in knee osteoarthritis patients.Methods Patients of knee osteoarthritis in The People’s Hospital of Taihe from Feb.2017 to Feb. 2018 were divided into two groups according to the treatment method.Patients of the control group(n＝75)were treat? ed with sodium hyaluronate knee cavity injection.Patients of the herbal fumigation group(n＝63)were treated with herbal fumiga? tion combined with sodium hyaluronate knee cavity injection.After 5 weeks of treatment，the clinical efficacy，knee joint function， pain and adverse reactions between the two groups were observed.The patients with cure and effective clinical efficacy were fol?lowed up for 1 year.Results 5 weeks after treatment，compared with the control group，the total effective rate［98.4% vs. 88.0%，P＜ 0.05］and Lysholm knee scores in the herbal fumigation group were significantly increased［(86.9±5.1)vs.(75.6±6.2)，P＜0.05］， while the visual analogue scores were decreased［( 3.2±0.5)vs.(4.6±0.9)，P＜0.05］.The incidence of adverse reactions were de? creased(6.3% vs. 18.7%，P＜0.05).The results of follow?up showed that the total recurrence rate and cumulative recurrence rate inherbal fumigation group were significantly lower than the control group within one year after treatment(P＜0.05).Conclusion Herbal fumigation combined with sodium hyaluronate injection can effectively improve the knee joint function，reduce the recur? rence rate within 1 year after treatment of knee osteoarthritis patients，which prognosis effect is good. |
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