| 王何刚,杨克,王世英.序贯通气转换标准差异对重症肺炎伴呼吸衰竭病人病程及临床预后的影响[J].安徽医药,2020,24(7):1356-1358. |
| 序贯通气转换标准差异对重症肺炎伴呼吸衰竭病人病程及临床预后的影响 |
| Influence of sequential ventilation conversion standard difference on the disease course and clinical prognosis of patients with severe pneumonia combined with respiratory failure |
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| DOI：10.3969/j.issn.1009?6469.2020.07.021 |
| 中文关键词: 呼吸，人工 /方法 呼吸功能不全 序贯通气转换 肺部感染控制窗 自主呼吸试验 肺炎 呼吸衰竭 病程 预后 |
| 英文关键词: Respiration,artificial/methods Respiratory insufficiency Sequential ventilation conversion Pulmonary infection control window Spontaneous breathing experiments Pneumonia Respiratory failure Disease course Prognosis |
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| 中文摘要: |
| 目的探讨序贯通气转换标准差异对重症肺炎伴呼吸衰竭病人病程及临床预后的影响。方法选取武汉市第五医院 2016年 1月至 2018年 1月收治重症肺炎伴呼吸衰竭病人共 100例，以随机数字表法分为控制窗组( 50例)和呼吸试验组( 50例)分别根据肺部感染控制窗( PICW)和自主呼吸试验( SBT)确定序贯通气转换时机；比较两组病人通气用时、重症监护病房(ICU)，住院用时、住院总用时、再插管率、呼吸机相关性肺炎( VAP)发生率及院内死亡率。结果呼吸试验组病人有创通气用时、机械通气总用时、 ICU住院用时及住院总用时分别为( 7.65±1.48)d，(10.10±2.10)d，(14.22±2.05)d，(20.74±3.51)d，均显著短于控制窗组的( 12.93±2.04)d，(16.33±3.17)d，(22.14±3.60)d，(29.47±4.64)d，P＜0.05；呼吸试验组病人再插管率和 VAP发生率分别为 14.00%，8.00%，显著低于控制窗组的 38.00%，24.00%(P＜0.05)；同时两组病人院内死亡率比较差异无统计学意义( P＞0.05)。结论针对重症肺炎伴呼吸衰竭病人根据 SBT确定序贯通气转换时机可有效缩短通气时间，加快病情康复进程，预防再插管和 VAP发生，价值优于 PICW。 |
| 英文摘要: |
| Objective To investigate the influence of sequential ventilation conversion standard difference on the disease courseand clinical prognosis of patients with severe pneumonia combined with respiratory failure. Methods 100 patients with severepneumonia combined with respiratory failure admitted to the Fifth Hospital of Wuhan from January 2016 to January 2018 were di?vided into a control window group(50 cases)and a respiratory test group(50 cases)by random number table method.Determinethe timing of sequential ventilation conversion according to the Pulmonary Infection Control Window(PICW) and Spontaneous Breathing Test(SBT)； and the ventilation time，ICU hospitalization time，total hospitalization time，re?intubation rate，VAP rate and hospital mortality of both groups were compared.Results The invasive ventilation time，total mechanical ventilation time，ICU hos? pitalization time and total hospitalization time of breathing test group were(7.65±1.48)d，(10.10±2.10)d，(14.22±2.05)d，(20.74±3.51)d，which were significantly shorter than control window group which respectively were(12.93±2.04)d，(16.33±3.17)d，(22.14± 3.60)d |
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