| 谢丹丹,袁良津.帕金森病 20例的错误记忆评估[J].安徽医药,2020,24(7):1370-1373. |
| 帕金森病 20例的错误记忆评估 |
| The assessment of false memory in 20 patients with Parkinson’s disease |
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| DOI：10.3969/j.issn.1009?6469.2020.07.025 |
| 中文关键词: 帕金森病 记忆障碍 回忆 联想学习 语言试验 谵妄，痴呆，遗忘，认知障碍 知道感 神经心理学 |
| 英文关键词: Parkinson’s disease Memory disorders Mental recall Association learning Language tests Delirium,dementia,amnestic,cognitive disorders Feeling?of?knowing Neuropsychology |
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| 中文摘要: |
| 目的探讨帕金森病( PD)病人错误记忆改变的神经心理学特征，研究 PD病人错误记忆产生可能机制。方法选择 2016年 10月至 2019年 10月在安徽医科大学附属安庆市立医院神经内科病房住院的帕金森病病人 20例，使用集中联想研究(Deese?Roediger?Mcdermott，DRM)范式和知道感判断( Feeling?Of?Knowing，FOK)范式，对 20例 PD病人和 20例教育程度等相匹配的健康人群进行研究。结果帕金森组关键诱饵的错误再认率 0.666(0.541，0.666)和 FOK的正确判断错误再认率(即高估)(0.209±0.050)均高于对照组相关键诱饵的错误再认率 0.500(0.500，0.500)和 FOK的正确判断错误再认率( 0.144±0.054)，均差异有统计学意义( Z＝-3.714，P＝0.000；t＝3.917，P＝0.000)；且关键诱饵的错误再认率与正确判断错误再认率呈正相关( r＝0.790，P＝0.000)。结论 PD病人关键诱饵的错误记忆较 HC组高，且对自身再认能力高表现为高估，记忆监测障碍可能是导致其错误记忆增加的重要因素。 |
| 英文摘要: |
| Objective To investigate neuropsychological characteristics of false memory in patients with Parkinson’s disease(PD)， and further explore possible mechanisms of the false memory.Methods From October 2016 to October 2019，twenty patients withPD hospitalized in the department of neurology in Anqing Hospital Affiliated to Anhui Medical University and twenty healthy con?trols were recruited in this study.All participants completed the Deese?Roediger?McDermott paradigm(DRM)and Feeling?Of?Know? ing(FOK) task.Results In the PD group，the incorrect recognition rate of critical lures［median＝0.666(P25＝0.541，P75＝ 0.666)］in DRM task was higher than that［M(P25，P75)＝0.500(0.500，0.500)］in the healthy controls group and also the rate of correct judgment but false recognition(overrate)( 0.209±0.050)in FOK task was higher than that(0.144±0.054)in the healthy controls group.There were significant differences between the two groups(Z＝-3.714，P＝0.000；t＝3.917，P＝0.000).The incorrect recognition rate of critical lures were positively correlated with FOK of correct judgment but false recognition in PD group(r＝0.790，P |
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