| 詹士江,叶敏捷,廖荣丰.18～30岁近视病人眼生物测量参数的分布及相关性分析[J].安徽医药,2020,24(11):2170-2173. |
| 18～30岁近视病人眼生物测量参数的分布及相关性分析 |
| Distributionandcorrelation analysis of ocular biometric parameters in myopia patients aged18?30 years |
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| DOI：10.3969/j.issn.1009?6469.2020.11.013 |
| 中文关键词: 近视 眼轴长度 角膜曲率 角膜曲率半径 前房深度 成年人 |
| 英文关键词: Myopia Axis length Corneal curvature Corneal curvature radius Anterior chamber depth Adult |
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| 中文摘要: |
| 目的分析 18～30岁近视病人眼生物测量参数的分布及相互之间相关性。方法选取 2017年 1月至 2018年 6月安徽医科大学第一附属医院行准分子激光术前检查的 18～30岁近视病人 2 075例，均选择右眼进行散瞳验光，并按等效屈光度(SE)分为低度近视组(A组，＜-3D，349只眼)中度近视组(B组， -3D～-6D，1 140只眼)高度近视组(C组，＞-6D，586只眼)。采用眼前节全景仪(Pentacam)测量眼轴(AL)、角，膜曲率半径(CR)及前房深度(ACD)计算，平均角膜曲率(K)及角膜曲率半径比(AL/CR)。结果三组年龄差异无统计学意义。随着 SE的增加， AL、K、AL/CR均逐渐，增加， CR值逐渐降低，三组均差异有统计学意义(P＜0.001)。各组间 ACD差异无统计学意义(P＝0.477)。 Spearman相关性分析中 SE与 CR呈线性正相关，与 AL及 AL/CR均呈线性负相关(r分别为 0.121，-0.597，-0.782，均 P＜0.001)。在与 AL相关性分析中， AL与 K呈线性负相关(r＝ -0.514，P＜0.001)与 CR及 ACD呈线性正相关(r分别为 0.514，0.296，P＜0.001)。在与 AL/CR相关性分析中， AL/CR与 CR呈线性负相关(r＝-0.33，5，P＜0.001)与 AL、ACD呈线性正相关(r为 0.592，0.289，P均＜ 0.001)。随着 SE逐渐增加， AL/CR与 CR相关性逐渐减弱，与 AL相关性逐渐增，强。结论 18～30岁近视病人的屈光度主要与眼轴、角膜曲率(半径)及 AL/CR有关，前房深度相关性不显著。其中 AL/CR对屈光状态的预测优于其他屈光参数。 AL及角膜曲率之间可能存在一个相互作用的机与制，通过改变角膜屈光力使屈光状态偏向正视。 |
| 英文摘要: |
| Objective To study the distribution and correlation of eye biometric parameters in myopia patients aged 18?30 years. Methods Two thousand and seventy?five young myopic patients(18?30 years old)who underwent preoperative excimer laser ex?aminations in the First Affiliated Hospital of Anhui Medical University from January 2017 to June 2018 were selected.The patientsreceived mydriatic refraction in the right eye，and were divided into low myopia group(group A，＜-3D，349 eyes)，moderate myo? pia group(group B，-3D to -6D，1 140 eyes)and high myopia group(group C，＞-6D，586 eyes)according to spherical equiva? lent(SE)of right eyes.Pentacam was used to measure axial length(AL)，corneal radius of curvature(CR)ratio and anterior cham? ber depth(ACD).Then，average keratometric reading(K)and the ratio of corneal curvature radius to corneal curvature radius(AL/ CR)were calculated.SPSS 23.0 was used for statistical analysis.Results There was no significant difference in age among the three groups.With the increase of SE，AL，K and AL/CR increased and CR values decreased gradually.There were significant differ? ences among the three groups(all P＜0.001).However，no significant difference in ACD was found among groups(P＝0.477).The results of spearman correlation analysis illustrated that SE was linear positively correlated with CR and linear negatively correlatedwith AL and AL/CR(r were0.121，-0.597，-0.782，respectively，all P＜0.001).There was a significant negative correlation between AL and K(r＝-0.514，P＜0.001)，and positive correlations between AL and CR，ACD(r were 0.514，0.296，respectively，all P＜0.001).AL/CR was negatively correlated with CR(r＝-0.335，P＜0.001)，and positively correlated with AL and ACD(r was 0.592 and 0.289 respectively，all P＜0.001).With the increase of SE，the correlation between AL/CR and CR weakened gradually，and the correlation with AL gradually increased.Conclusion The axis，corneal curvature(radius)and AL/CR，but not the anterior cham? ber depth，are associated with refractive status of young adults with myopia.AL/CR ratio can betterpredict the total variance in SEthan AL or CR alone.There may be an interaction mechanism between AL and corneal curvature，which makes corneal refractive state deflect to emmetropia by changing corneal refractive power. |
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